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Research ArticleResearch Article

Clinicopathological Characteristics as Predictive Factrs for Lymph Node Metastasis in Submucosal Gastric Cancer

Caigang Liu, Ping Lu, Yang Lu, Lua Li, Ruishan Zhang, Huimian Xu, Shubao Wang and Junqing Chen
Chinese Journal of Clinical Oncology August 2007, 4 (4) 237-240; DOI: https://doi.org/10.1007/s11805-007-0237-y
Caigang Liu
Department of Oncology, First Affiliated Hospital of China Medial University, Shenyang 110001, China.
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Ping Lu
Department of Oncology, First Affiliated Hospital of China Medial University, Shenyang 110001, China.
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  • For correspondence: Luping{at}mail.cmu.edu.cn
Yang Lu
Department of Oncology, First Affiliated Hospital of China Medial University, Shenyang 110001, China.
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Lua Li
Department of Oncology, First Affiliated Hospital of China Medial University, Shenyang 110001, China.
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Ruishan Zhang
Department of Oncology, First Affiliated Hospital of China Medial University, Shenyang 110001, China.
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Huimian Xu
Department of Oncology, First Affiliated Hospital of China Medial University, Shenyang 110001, China.
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Shubao Wang
Department of Oncology, First Affiliated Hospital of China Medial University, Shenyang 110001, China.
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Junqing Chen
Department of Oncology, First Affiliated Hospital of China Medial University, Shenyang 110001, China.
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    Table 1.

    Univariate analysis of potential risk characteristics for lymph node metastasis (cases).

    Lymph node metastasis positive rate (%)P
    SexNS
        Male21.05 (20/95)
        Female28.57 (10/35)
    AgeNS
        ≤ 60 years25.64 (20/78)
        > 60 years23.81 (10/52)
    Family medical historyNS
        Positive47.37 (9/28)
        Negative19.23 (21/102)
    History of past illnessNS
        Positive22 (11/50)
        Negative23.75 (19/80)
    Number of tumorsNS
        Single24.39 (30/123)
        Multitude0 ( 0/7)
    Tumor locationNS
        Upper third14.29 (1/7)
        Middle third30.43 (7/23)
        Lower third22 (22/100)
    Tumor size0.003
        ≤ 2 cm3.45 (1/29)
        > 2 cm28.71 (29/101)
    Macroscopic typeNS
        I50 (1/2)
        II25.32 (20/79)
        III18.37 (9/49)
    Histologic type0.009
        Differentiated12.90 (8/62)
        Undifferentiated32.35 (22/68)
    Growth patternNS
        Massive23.33 (7/30)
        Nest12.77 (6/47)
        Diffuse18.87 (10/53)
    • NS, not significant

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    Table 2.

    Multivariate analysis of potential risk factors for lymph node metastasis.

    Variables*Odds ratio95% Confidence intervalP
    Tumor size (<2 cm or ≤2 cm)9.4981.214~74.3350.032
    Histologic type (differentiated or undifferentiated)2.9221.135~7.5240.026
    • ↵* Significant factors identified by univariate analysis were included in the multivariate analysis.

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Cancer Biology and Medicine: 4 (4)
Chinese Journal of Clinical Oncology
Vol. 4, Issue 4
August 2007
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Clinicopathological Characteristics as Predictive Factrs for Lymph Node Metastasis in Submucosal Gastric Cancer
Caigang Liu, Ping Lu, Yang Lu, Lua Li, Ruishan Zhang, Huimian Xu, Shubao Wang, Junqing Chen
Chinese Journal of Clinical Oncology Aug 2007, 4 (4) 237-240; DOI: 10.1007/s11805-007-0237-y

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Clinicopathological Characteristics as Predictive Factrs for Lymph Node Metastasis in Submucosal Gastric Cancer
Caigang Liu, Ping Lu, Yang Lu, Lua Li, Ruishan Zhang, Huimian Xu, Shubao Wang, Junqing Chen
Chinese Journal of Clinical Oncology Aug 2007, 4 (4) 237-240; DOI: 10.1007/s11805-007-0237-y
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Keywords

  • early gastric cancer
  • lymph node
  • metastasis
  • clinicopathological characteristics
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