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Research ArticleResearch Article

A Study of the Number and Metastatic Status of Lymph Nodes Ressected During Non—Small Cell Lung Cancer Surgery

Xuefeng Kan and Changli Wang
Chinese Journal of Clinical Oncology April 2007, 4 (2) 121-125; DOI: https://doi.org/10.1007/s11805-007-0121-9
Xuefeng Kan
Department of Pulmonary Tumors, Tianjin Medical University Cancer Hospital, Tianjin 300060, China.
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  • For correspondence: kanxf{at}126.com
Changli Wang
Department of Pulmonary Tumors, Tianjin Medical University Cancer Hospital, Tianjin 300060, China.
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  • Survival curves for patients with more and less than 6 LNs resected. The 5-year survival rates were 29.4% and 24.8%.
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    Fig.1.

    Survival curves for patients with more and less than 6 LNs resected. The 5-year survival rates were 29.4% and 24.8%.

  • Survival curves of patients with metastatic LNs in different regions. The 5-year survival rates of N1, skip N2 and continue N2 patients were 12.4%, 14.7% and 7.0%.
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    Fig.2.

    Survival curves of patients with metastatic LNs in different regions. The 5-year survival rates of N1, skip N2 and continue N2 patients were 12.4%, 14.7% and 7.0%.

  • Survival curves of patients with single-station metastatic LNs and multiple-station metastatic LNs. The 5-year survival rates were 13.9% and 7.3%.
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    Fig.3.

    Survival curves of patients with single-station metastatic LNs and multiple-station metastatic LNs. The 5-year survival rates were 13.9% and 7.3%.

  • Survival curves of patients with a different number of metastatic LNs. The 5-year survival rates of 1~2 LNs and more than 2 LNs were 12.4% and 8.3%.
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    Fig.4.

    Survival curves of patients with a different number of metastatic LNs. The 5-year survival rates of 1~2 LNs and more than 2 LNs were 12.4% and 8.3%.

  • Survival curves of patients with a different metastatic ratio of LNs. The 5-year survival rate were 16.7%, 13.5%, 6.8% and 2.0%, respectively.
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    Fig.5.

    Survival curves of patients with a different metastatic ratio of LNs. The 5-year survival rate were 16.7%, 13.5%, 6.8% and 2.0%, respectively.

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    Table 1.

    Clinical characteristics of 1,575 patients with NSCLC.

    CharacteristicsNumberPercentage (%)
    GenderMale109069.2
    Female48530.8
    Age<70 years141790.0
    ≤70 years15810.0
    Smoking historyYes101264.3
    No56335.7
    The type of histologySquamous cell carcinoma91458.0
    Non-Squamous cell carcinoma66142.0
    Stage I85254.0
    Clinical stageStage II33021.0
    Stage III39325.0
    N090257.3
    N StageN132220.4
    N235122.3
    Number of LNs resected≤664941.2
    >692658.8
    089757.3
    Number of metastatic LNs1~243727.7
    >224115.3
    ≤25%27039.8
      Metastatic ratio of LNs25~50%20129.6
    50~75%8011.8
    >7512718.7
    No metastatic LNs90257.3
    The distribution area of metastatic LNs*N132220.4
      Skip N216110.2
      Continue N219012.1
    • ↵* Skip N2 only included metastatic LNs in the mediastinum and without metastatic LNs in the region of N1; continue N2 included metastatic LNs in the mediastinum and the region of N1.

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    Table 2.

    Results of univariate analysis of 1,575 patients with NSCLC.

    VariableFavorable factorsUnfavorable factorsP value
    Age<70 years≥70 years0.039
    SexMaleFemale0.902
    Smoking historyYesNo0.416
    Histologic typeSquamous carcinomaNon-squamous carcinoma0.041
    Clinical stageStage IStage II0.000
    Stage IStage III0.000
    Stage IIStage III0.013
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Cancer Biology and Medicine: 4 (2)
Chinese Journal of Clinical Oncology
Vol. 4, Issue 2
April 2007
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A Study of the Number and Metastatic Status of Lymph Nodes Ressected During Non—Small Cell Lung Cancer Surgery
Xuefeng Kan, Changli Wang
Chinese Journal of Clinical Oncology Apr 2007, 4 (2) 121-125; DOI: 10.1007/s11805-007-0121-9

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A Study of the Number and Metastatic Status of Lymph Nodes Ressected During Non—Small Cell Lung Cancer Surgery
Xuefeng Kan, Changli Wang
Chinese Journal of Clinical Oncology Apr 2007, 4 (2) 121-125; DOI: 10.1007/s11805-007-0121-9
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Keywords

  • lung neoplasms
  • lymphonectomy
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  • NSCLC

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