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Research ArticleResearch Article

The Inhibitory Effect of Oridonin on the Growth of Fifteen Human Cancer Cell Lines

Junhui Chen, Shaobin Wang, Dongyang Chen, Guisheng Chang, Qingfeng Xin, Shoujun Yuan and Zhongying Shen
Chinese Journal of Clinical Oncology February 2007, 4 (1) 16-20; DOI: https://doi.org/10.1007/s11805-007-00016-9
Junhui Chen
1Department of Oncology, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, China.
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  • For correspondence: chenjh{at}stu.edu.cn
Shaobin Wang
1Department of Oncology, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, China.
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Dongyang Chen
1Department of Oncology, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, China.
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Guisheng Chang
1Department of Oncology, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, China.
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Qingfeng Xin
1Department of Oncology, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, China.
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Shoujun Yuan
2Pharmacology Laboratory, Institute of Radiation Medicine, Military Medical Sciences Academy of Chinese PLA, Beijing 100270, China
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Zhongying Shen
3Department of Pathology, Shantou University Medical College, Shantou 515031, China.
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  • Article
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REFERENCES

  1. ↵
    The Pharmacology and Medicinal Chemistry Group of Henan Institute of Medical Sciences. A new anti-tumorigenic substance-rubescensin. Chin Sci Bull. 1978;23:53-56 (Chinese).
    OpenUrl
  2. ↵
    1. Fan HY,
    2. Sun HD,
    3. Huang JH, et al.
    Studies on the chemistry of Rubescensine B. J Henan Medical College 1979; 14:14-16 (Chinese).
    OpenUrl
  3. ↵
    1. Sun HD,
    2. Chao JH,
    3. Lin ZW, et al.
    The structure of rubescensine C. Chem Pharm Bull 1982;30:341-343.
    OpenUrl
  4. ↵
    1. Sun HD,
    2. Zhao QZ,
    3. Fujita T, et al.
    The structure of rubescensin D. Phgtochemistry 1992;31:1418-1419.
    OpenUrl
  5. ↵
    1. Lin CJ,
    2. Zhao ZH
    . Studies on structure of rubescensine E. Chin J Chin Materia Medica. 1997;22:612-613 (Chinese).
    OpenUrl
  6. ↵
    1. Feng CW,
    2. Pan XL,
    3. Guo JH, et al.
    Study on inhibition of human HL-60 cells by oridonin. J Zhejiang College of TCM. 2000;24:47-48 (Chinese).
    OpenUrl
  7. ↵
    1. Liu JJ,
    2. Wu XY,
    3. Lu HL, et al.
    Antiproliferation effect of oridonin on HL-60 cells and its mechanism. Chin Med Sci J 2004;19:134-137.
    OpenUrlPubMed
  8. ↵
    1. Li RF,
    2. Wang QD
    . Regulation of telomerase activity and cell cycle by oridonin in K562 cells. Henan J Oncol 2004;17:305-307 (Chinese).
    OpenUrl
  9. ↵
    1. Liu JJ,
    2. Huang RW,
    3. Lin DJ, et al.
    Oridonin-induced apoptosis in leukemia K562 cells and its mechanism. Neoplasma 2005;52:225-230.
    OpenUrlPubMed
  10. ↵
    1. Liu JJ,
    2. Huang RW,
    3. Lin DJ, et al.
    Antiproliferation effect of oridonin on HPB-ALL cells and its mechanisms of action. Am J Hematol 2006;81:86-94.
    OpenUrlCrossRefPubMed
  11. ↵
    1. Ikezoe T,
    2. Chen SS,
    3. Tong XJ, et al.
    Oridonin induces growth inhibition and apoptosis of a variety of human cancer cells. Int J Oncol 2003;23:1187-1193.
    OpenUrlPubMedWeb of Science
  12. ↵
    1. Ikezoe T,
    2. Yang Y,
    3. Bandobashi K, et al.
    Oridonin, a diterpen-oid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-KB signal pathways. Mol Cancer Ther 2005;4:578-586.
    OpenUrlAbstract/FREE Full Text
  13. ↵
    1. Li XT,
    2. Lin C,
    3. Li PY, et al.
    Comparative study on the sensitivties of seven human cancer cell lines to rubescensine A. Acta Pharmaceutica Sinica. 1985;20:243-246 (Chinese).
    OpenUrl
  14. ↵
    1. Zhang JF,
    2. Liu JJ,
    3. Liu PQ, et al.
    Oridonin inhibits cell growth by induction of apoptosis on human hepatocelluar carcinoma BEL-7402 cells. Hepatol Res 2006;35:104-110.
    OpenUrlPubMed
  15. ↵
    1. Xiao DJ,
    2. Zhu GC,
    3. Wang XL, et al.
    Study of the cytotoxic effect of hypericum japonicum thunb and oridonin on the human nasopharyngeal carcinoma cell line CNE. J Qiqihaer Medical College 2005;26:1396-1397 (Chinese).
    OpenUrl
  16. ↵
    1. Liu JJ,
    2. Huang RW,
    3. Lin DJ, et al.
    Antiproliferative effects of oridonin on SPC-A-1 cells and its mechanism of action. J Int Med Res 2004;32:617-625.
    OpenUrlCrossRefPubMedWeb of Science
  17. ↵
    1. Zhang CL,
    2. Wu LJ,
    3. Tashiro SI, et al.
    Oridonin induces A375-S2 cell apoptosis via BAX-regulated caspase pathway activation dependent on the cytochrome C/Capase-9 apoptosome. J Asian Nat Prod Res 2004;6:127-138.
    OpenUrlPubMed
  18. ↵
    1. Chen S,
    2. Gao J,
    3. Halicka H D, et al.
    The cytostatic and cytotoxic effects of oridonin (rubescenin), a diterpenoid from Rabdosia rubescens, on tumor cells of different lineage. Int J Oncol 2005;26:579-588.
    OpenUrlPubMed
  19. ↵
    1. Cui Q,
    2. Tashiro SI,
    3. Onodera S, et al.
    Augmentation of orido-nin induced apoptosis observed with reduced autophagy. J Pharmacol Sci 2006;101:230-239.
    OpenUrlCrossRef
  20. ↵
    1. Wang RL,
    2. Fan KS,
    3. Zhao GX, et al.
    Clinical studies of oridonin on therapy the malignant tumor. Papers on antitumor studies of Rabdosia rubescens. 1990, 8-21 (Chinese).
  21. ↵
    1. Zhang TM,
    2. Wang MY,
    3. Lin C
    . The effect of oridonin on the cytokinetic of ECA cells. J Henan Medical College. 1982;17:7-12 (Chinese).
    OpenUrl
    1. Wang MY,
    2. Lin C,
    3. Zhang TM
    . Cytokinetic effects of oridonin on leukemia L1210 cells. Acta Pharmacol Sin 1985;6:195-197.
    OpenUrl
  22. ↵
    1. Wang MY,
    2. Lin C,
    3. Zhang TM
    . Effects of oridonin on DNA RNA and protein syntheses of leukemia 1210 cells studied by autoradiography. Acta Pharmacol Sin 1987;8:164-165.
    OpenUrl
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Cancer Biology and Medicine: 4 (1)
Chinese Journal of Clinical Oncology
Vol. 4, Issue 1
February 2007
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The Inhibitory Effect of Oridonin on the Growth of Fifteen Human Cancer Cell Lines
Junhui Chen, Shaobin Wang, Dongyang Chen, Guisheng Chang, Qingfeng Xin, Shoujun Yuan, Zhongying Shen
Chinese Journal of Clinical Oncology Feb 2007, 4 (1) 16-20; DOI: 10.1007/s11805-007-00016-9

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The Inhibitory Effect of Oridonin on the Growth of Fifteen Human Cancer Cell Lines
Junhui Chen, Shaobin Wang, Dongyang Chen, Guisheng Chang, Qingfeng Xin, Shoujun Yuan, Zhongying Shen
Chinese Journal of Clinical Oncology Feb 2007, 4 (1) 16-20; DOI: 10.1007/s11805-007-00016-9
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