Table of Contents

Special Issue on Microbiota and Cancer Guest Editor: Professor Jun Yu, Institute of Digestive Disease, Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong SAR, China

• Editorial

  • Open Access

    Gut microbiome: an emerging player and therapeutic target in cancer

    Jun Yu

    Cancer Biology & Medicine May 2026, 23 (5) 559-560; DOI: https://doi.org/10.20892/j.issn.2095-3941.2026.0349

• Reviews

  • Open Access

    How the gut microbiome affects the immunotherapy response in hepatocellular carcinoma

    Mengrui Wu, Yating Zhang and Jun Yu

    Cancer Biology & Medicine May 2026, 23 (5) 561-579; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0761
  • Open Access

    Microbiota-host interaction in colorectal cancer: emerging computational technology, multi-omics integration, and mechanisms

    Yinghong Lu and Jun Yu

    Cancer Biology & Medicine May 2026, 23 (5) 580-595; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0762
  • Open Access

    Probiotics in colorectal cancer: mechanisms, biomarkers, and adjunct strategies

    Zihe Xu, Lan Mu, Hao Su, Xiaoting Zhang, Haiyun Shang, Zhuotian Li, Matthew Tak Vai Chan, William Ka Kei Wu and Huarong Chen

    Cancer Biology & Medicine May 2026, 23 (5) 596-614; DOI: https://doi.org/10.20892/j.issn.2095-3941.2026.0133
  • Open Access

    Tumor-resident bacteria in gastrointestinal cancers: from regulatory mechanisms to clinical implications

    Ying Zhang, Bingyu Tan, Qianying Zhou, Lixia Xu and Lei Zhou

    Cancer Biology & Medicine May 2026, 23 (5) 615-636; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0686
  • Open Access

    Animal models and pathogenesis of gastric cancer: from premalignant conditions-to-metastasis

    Yumeng Pan, Licong Zhao and Jingyuan Fang

    Cancer Biology & Medicine May 2026, 23 (5) 637-656; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0576
  • Open Access

    Microbial reprogramming of immunogenic cell death: a new paradigm in tumor immunotherapy

    Yilin Li, Huiyue Zhang, Yun Feng, Kun Fang, Yue Wang, Yuhang Zhou, Tao Sun and Junnan Xu

    Cancer Biology & Medicine May 2026, 23 (5) 657-677; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0769
  • Open Access

    Gut microbiota and pancreatic cancer: tumorigenesis, progression, and clinical applications

    Chuxiong Cheng, Jingsong Wang, Jin Xie, Hanlin Yin, Zhihang Xu, Yuqi Xie, Taochen He, Zhenlai Jiang, Yu Wang, Wenchuan Wu, Wenhui Lou, Jie Wang, Liang Liu and Ning Pu

    Cancer Biology & Medicine May 2026, 23 (5) 678-702; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0650

• Letter

  • Open Access

    Antibiotics and probiotics differentially shape immunotherapy outcomes in non-small cell lung cancer

    Shuling Ma, Zijun Zhai, Rui Ding, Shijie Shang, Xinyi Liang, Shan Yin, Haofeng Lin, Guomeng Sha, Ran Zhang, Jinming Yu, Qian Song and Dawei Chen

    Cancer Biology & Medicine May 2026, 23 (5) 703-716; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0844

• Original Articles

  • Open Access

    Dietary nitrate drives gastritis by modulating gastric microbiota and metabolites

    Lanping Jiang, Tianhui Li, Jiayu Wu, Harry Cheuk Hay Lau, Chi Chun Wong, Xingyu Zhou, Alvin Ho Kwan Cheung, Qinyao Wei, Jing Ren, Xiang Zhang, Qing Li, Yongzhan Nie and Jun Yu

    Cancer Biology & Medicine May 2026, 23 (5) 717-736; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0679
  • Open Access

    Bifidobacterium animalis suppresses melanoma progression and activates anti-tumor immunity by inhibiting YAP1 expression in CD8⁺ T cells

    Chengyi Li, Xuehua Zhang, Yichen Yang, Haotian Zeng, Yanqiang Shi, Jinjin Zhang, Lingjun Liu, Chenwei Zhu, Zhiwen Zhang, Chao Li, Xudong Wang, Xiaowu Bai, Haijun Deng and Qing Li

    Cancer Biology & Medicine May 2026, 23 (5) 737-754; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0652
  • Open Access

    Comprehensive microbiome profiling reveals mucosal microbiome heterogeneity in patients with left- and right-sided colorectal neoplasia

    Sunny H. Wong, Thomas N.Y. Kwong, Ru Zhang, Thomas Y.T. Lam, Andrew M.Y. Ho, Wing Wah Leung, Xing Kang, Harry C.H. Lau, Eagle S.H. Chu, Marc T.L. Wong, Louis H.S. Lau, Rashid N.S. Lui, Raymond S.Y. Tang, James Y.W. Lau, Simon S.M. Ng, Jun Yu and Joseph J.Y. Sung

    Cancer Biology & Medicine May 2026, 23 (5) 755-768; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0846
  • Open Access

    SARS-CoV-2 infection in brain tumors and the association with alterations in the tumor immune microenvironment

    Weikang Chen, Haojie Bai, Maoling Tian, Yanxia Huang, Depei Li, Luyao Wu, Wei Li, Lei Zhou, Wange Lu, Xiaoxing Li, Linyi Liu and Xiaobing Jiang

    Cancer Biology & Medicine May 2026, 23 (5) 769-784; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0468