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Research ArticleOriginal Article
Open Access

Safety and efficacy of intraoperative radiation therapy using a low-energy X-ray source for resectable pancreatic cancer: an interim evaluation of an ongoing prospective phase II study

Xingyun Chen, Shuo Li, Chuntao Gao, Wei Wang, Haorui Li, Yuxiao Liu, Rui Liu and Jihui Hao
Cancer Biology & Medicine January 2025, 22 (1) 67-76; DOI: https://doi.org/10.20892/j.issn.2095-3941.2024.0287
Xingyun Chen
1Department of Pancreatic Cancer, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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Shuo Li
1Department of Pancreatic Cancer, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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Chuntao Gao
1Department of Pancreatic Cancer, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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Wei Wang
2Department of Radiation Oncology, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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Haorui Li
1Department of Pancreatic Cancer, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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Yuxiao Liu
1Department of Pancreatic Cancer, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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Rui Liu
3Department of Gastrointestinal Oncology, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin Key Laboratory of Digestive Cancer, Tianjin 300060, China
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  • ORCID record for Rui Liu
  • For correspondence: liurui9003{at}163.com haojihui{at}tjmuch.com
Jihui Hao
1Department of Pancreatic Cancer, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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  • For correspondence: liurui9003{at}163.com haojihui{at}tjmuch.com
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Article Information

vol. 22 no. 1 67-76
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2024.0287

Published By 
Cancer Biology & Medicine
History 
  • Received July 25, 2024
  • Accepted November 25, 2024
  • Published online February 4, 2025.

Article Versions

  • previous version (January 3, 2025 - 00:13).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright: © 2025, The Authors This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License.

Author Information

  1. Xingyun Chen1,*,
  2. Shuo Li1,*,
  3. Chuntao Gao1,
  4. Wei Wang2,
  5. Haorui Li1,
  6. Yuxiao Liu1,
  7. Rui Liu3⇑ and
  8. Jihui Hao1⇑
  1. 1Department of Pancreatic Cancer, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
  2. 2Department of Radiation Oncology, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
  3. 3Department of Gastrointestinal Oncology, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin Key Laboratory of Digestive Cancer, Tianjin 300060, China
  1. Correspondence to: Rui Liu and Jihui Hao, E-mail: liurui9003{at}163.com and haojihui{at}tjmuch.com
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Funding

  • Tianjin Science and Technology Commission key project

    21JCZDJC00980
  • Tianjin Science and Technology Commission project

    22ZXJBSY00030
  • Tianjin Health Research project

    TJWJ2022MS007

This work was supported by the Tianjin Science and Technology Commission key project (Grant No. 21JCZDJC00980), Tianjin Science and Technology Commission project (Grant No. 22ZXJBSY00030), and Tianjin Health Research project (Grant No. TJWJ2022MS007).

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Cancer Biology & Medicine
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Safety and efficacy of intraoperative radiation therapy using a low-energy X-ray source for resectable pancreatic cancer: an interim evaluation of an ongoing prospective phase II study
Xingyun Chen, Shuo Li, Chuntao Gao, Wei Wang, Haorui Li, Yuxiao Liu, Rui Liu, Jihui Hao
Cancer Biology & Medicine Jan 2025, 22 (1) 67-76; DOI: 10.20892/j.issn.2095-3941.2024.0287

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Safety and efficacy of intraoperative radiation therapy using a low-energy X-ray source for resectable pancreatic cancer: an interim evaluation of an ongoing prospective phase II study
Xingyun Chen, Shuo Li, Chuntao Gao, Wei Wang, Haorui Li, Yuxiao Liu, Rui Liu, Jihui Hao
Cancer Biology & Medicine Jan 2025, 22 (1) 67-76; DOI: 10.20892/j.issn.2095-3941.2024.0287
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Subjects

  • Hepatobiliary and pancreatic cancer

Keywords

  • Resectable pancreatic cancer
  • intraoperative radiation
  • survival
  • complications
  • benefit group

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