Original ArticleOriginal Article
Open Access

Phase Ib study of anti-EGFR antibody (SCT200) in combination with anti-PD-1 antibody (SCT-I10A) for patients with RAS/BRAF wild-type metastatic colorectal cancer

Ming Bai, Yao Lu, Chunmei Shi, Jianwei Yang, Wei Li, Xianli Yin, Chenghui Huang, Lin Shen, Liangzhi Xie and Yi Ba
Cancer Biology & Medicine July 2024, 21 (7) 636-650; DOI: https://doi.org/10.20892/j.issn.2095-3941.2023.0301

Article Information

vol. 21 no. 7 636-650
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2023.0301
PubMed 
38148327
Published By 
Cancer Biology & Medicine
History 
  • Received August 15, 2018
  • Accepted November 22, 2023
  • Published online July 25, 2024.

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Copyright & Usage 
Copyright: © 2024, The Authors This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License.

Author Information

  1. Ming Bai1,*,
  2. Yao Lu1,*,
  3. Chunmei Shi2,
  4. Jianwei Yang3,
  5. Wei Li4,
  6. Xianli Yin5,
  7. Chenghui Huang6,
  8. Lin Shen7,
  9. Liangzhi Xie8 and
  10. Yi Ba1,9⇑
  1. 1Department of GI Medical Oncology, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin Key Laboratory of Digestive Cancer, Tianjin 300060, China
  2. 2Fujian Medical University Union Hospital, Fuzhou 350001, China
  3. 3Fujian Provincial Cancer Hospital, Fuzhou 350014, China
  4. 4Cancer Center, The First Hospital of Jilin University, Changchun 130021, China
  5. 5Department of Medical Oncology Gastroenterology and Urology, Hunan Cancer Hospital, Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, China
  6. 6Department of Oncology, The Third Xiangya Hospital, Central South University, Changsha 410013, China
  7. 7Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital and Institute, Beijing 100142, China
  8. 8Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing 100176, China
  9. 9Department of Cancer Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100010, China
  1. Correspondence to: Yi Ba, E-mail: bayi{at}tjmuch.com
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Funding

  • Tianjin Key Medical Discipline (Specialty) Construction Project

    TJYXZDXK-009A

  • National Natural Science Foundation of China

    82103677

  • National Science and Technology Major Projects of China

    2019ZX09732-001

This work was funded by Tianjin Key Medical Discipline (Specialty) Construction Project (Grant No. TJYXZDXK-009A), National Natural Science Foundation of China (Grant No. 82103677), and National Science and Technology Major Projects of China (Grant No. 2019ZX09732-001).

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