Research ArticleOriginal Article
Open Access

Efficacy and safety of anlotinib combined with the STUPP regimen in patients with newly diagnosed glioblastoma: a multicenter, single-arm, phase II trial

Shuzhen Lai, Peijing Li, Xiaohui Liu, Guihong Liu, Tieming Xie, Xing Zhang, Xiaoxuan Wang, Jing Huang, Yiqiang Tang, Zhigang Liu, Guoping Shen, Chaoming Li, Fangxiao Lu, Lei Wang, Fagui Jiang, Caixing Sun, Yuanyuan Chen and Ming Chen
Cancer Biology & Medicine May 2024, 21 (5) 433-444; DOI: https://doi.org/10.20892/j.issn.2095-3941.2023.0373

Article Information

vol. 21 no. 5 433-444
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2023.0373
PubMed 
38445445
Published By 
Cancer Biology & Medicine
History 
  • Received October 14, 2023
  • Accepted January 29, 2023
  • Published online May 27, 2024.

Article Versions

Copyright & Usage 
Copyright: © 2024, The Authors This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License.

Author Information

  1. Shuzhen Lai1,2,*,
  2. Peijing Li3,*,
  3. Xiaohui Liu4,
  4. Guihong Liu5,
  5. Tieming Xie6,
  6. Xing Zhang7,
  7. Xiaoxuan Wang7,
  8. Jing Huang8,
  9. Yiqiang Tang9,
  10. Zhigang Liu10,11,
  11. Guoping Shen12,
  12. Chaoming Li13,
  13. Fangxiao Lu6,
  14. Lei Wang3,
  15. Fagui Jiang14,
  16. Caixing Sun15,
  17. Yuanyuan Chen16,17⇑ and
  18. Ming Chen1,16,17⇑
  1. 1Department of Radiation Oncology, The Second Affiliated Hospital of Soochow University, Suzhou 215000, China
  2. 2Department of Radiation Oncology, Yuebei People’s Hospital Affiliated to the Medical College of Shantou University, Shaoguan 512026, China
  3. 3Department of Radiation Oncology, The Cancer Hospital of the University of Chinese Academy of Sciences [Zhejiang Cancer Hospital Institute of Basic Medicine and Cancer (IBMC)], Chinese Academy of Sciences, Hangzhou 310022, China
  4. 4Department of Radiation Oncology, The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 311403, China
  5. 5Department of Radiation Oncology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221004, China
  6. 6Department of Radiology, The Cancer Hospital of the University of Chinese Academy of Sciences [Zhejiang Cancer Hospital Institute of Basic Medicine and Cancer (IBMC)], Chinese Academy of Sciences, Hangzhou 310022, China
  7. 7State Key Laboratory of Translational Medicine and Innovative Drug Development, Jiangsu Simcere Diagnostics Co., Ltd, Nanjing 210000, China
  8. 8Department of Radiation Oncology, The Affiliated Huai’an First People’s Hospital of Nanjing Medical University, Huai’an 223399, China
  9. 9Department of Radiation Oncology, Jiangxi Cancer Hospital of Nanchang University, Nanchang 330029, China
  10. 10Department of Radiotherapy, Dongguan Institute of Clinical Cancer Research, Dongguan Key Laboratory of Precision Diagnosis and Treatment for Tumors, Affiliated Dongguan Hospital, Southern Medical University, Dongguan 523059, China
  11. 11The Cancer Center, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, China
  12. 12Department of Radiation Oncology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China
  13. 13Department of Oncology, Maoming People’s Hospital, Maoming 525000, China
  14. 14Department of Radiation Oncology, Kecheng District People’s Hospital, Quzhou 324003, China
  15. 15Department of Neurosurgery, The Cancer Hospital of the University of Chinese Academy of Sciences [Zhejiang Cancer Hospital Institute of Basic Medicine and Cancer (IBMC)], Chinese Academy of Sciences, Hangzhou 310022, China
  16. 16Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou 510060, China
  17. 17United Laboratory of Frontier Radiotherapy Technology of Sun Yat-sen University & Chinese Academy of Sciences Ion Medical Technology Co., Ltd, Guangzhou 510060, China
  1. Correspondence to: Yuanyuan Chen and Ming Chen, E-mail: chenyy2{at}sysucc.org.cn and chenming{at}sysucc.org.cn
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Funding

  • National Natural Science Foundation of China

    82272744

  • Natural Science Foundation of Guangdong Province

    2022A1515010814

  • Sun Yat-sen University Clinical Research 5010 Program

    2022008

This work was supported by the National Natural Science Foundation of China (Grant No. 82272744), Natural Science Foundation of Guangdong Province (Grant No. 2022A1515010814), and Sun Yat-sen University Clinical Research 5010 Program (Grant No. 2022008).

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