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Research ArticleOriginal Article

Exosomal miR-155 from gastric cancer induces cancer-associated cachexia by suppressing adipogenesis and promoting brown adipose differentiation via C/EPBβ

Ying Liu, Meng Wang, Ting Deng, Rui Liu, Tao Ning, Ming Bai, Guoguang Ying, Haiyang Zhang and Yi Ba
Cancer Biology & Medicine September 2022, 19 (9) 1301-1314; DOI: https://doi.org/10.20892/j.issn.2095-3941.2021.0220
Ying Liu
1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
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Meng Wang
1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
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Ting Deng
1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
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Rui Liu
1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
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Tao Ning
1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
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Ming Bai
1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
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Guoguang Ying
1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
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Haiyang Zhang
1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
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  • ORCID record for Haiyang Zhang
  • For correspondence: bayi{at}tjmuch.com zhanghaiyang{at}tmu.edu.cn
Yi Ba
1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
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  • ORCID record for Yi Ba
  • For correspondence: bayi{at}tjmuch.com zhanghaiyang{at}tmu.edu.cn
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Article Information

vol. 19 no. 9 1301-1314
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2021.0220

Published By 
Cancer Biology & Medicine
History 
  • Received April 9, 2021
  • Accepted July 21, 2021
  • Published online September 22, 2022.

Article Versions

  • previous version (July 15, 2022 - 07:16).
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Copyright & Usage 
Copyright: © 2022, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Author Information

  1. Ying Liu1,
  2. Meng Wang1,
  3. Ting Deng1,
  4. Rui Liu1,
  5. Tao Ning1,
  6. Ming Bai1,
  7. Guoguang Ying1,
  8. Haiyang Zhang1⇑ and
  9. Yi Ba1⇑
  1. 1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
  1. Correspondence to: Yi Ba and Haiyang Zhang, E-mail: bayi{at}tjmuch.com and zhanghaiyang{at}tmu.edu.cn
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Cancer Biology & Medicine: 19 (9)
Cancer Biology & Medicine
Vol. 19, Issue 9
15 Sep 2022
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Exosomal miR-155 from gastric cancer induces cancer-associated cachexia by suppressing adipogenesis and promoting brown adipose differentiation via C/EPBβ
Ying Liu, Meng Wang, Ting Deng, Rui Liu, Tao Ning, Ming Bai, Guoguang Ying, Haiyang Zhang, Yi Ba
Cancer Biology & Medicine Sep 2022, 19 (9) 1301-1314; DOI: 10.20892/j.issn.2095-3941.2021.0220

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Exosomal miR-155 from gastric cancer induces cancer-associated cachexia by suppressing adipogenesis and promoting brown adipose differentiation via C/EPBβ
Ying Liu, Meng Wang, Ting Deng, Rui Liu, Tao Ning, Ming Bai, Guoguang Ying, Haiyang Zhang, Yi Ba
Cancer Biology & Medicine Sep 2022, 19 (9) 1301-1314; DOI: 10.20892/j.issn.2095-3941.2021.0220
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Keywords

  • Exosomes
  • adipose mesenchymal stem cells
  • miR-155
  • cachexia
  • Gastric cancer

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