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Research ArticleOriginal Article

Loss of NEIL3 activates radiotherapy resistance in the progression of prostate cancer

Qiong Wang, Zean Li, Jin Yang, Shirong Peng, Qianghua Zhou, Kai Yao, Wenli Cai, Zhongqiu Xie, Fujun Qin, Hui Li, Xu Chen, Kaiwen Li and Hai Huang
Cancer Biology & Medicine August 2022, 19 (8) 1193-1210; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0550
Qiong Wang
1Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
2Department of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA
3Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
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Zean Li
1Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
3Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
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Jin Yang
3Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
4Department of Radiation Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
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Shirong Peng
1Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
3Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
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Qianghua Zhou
1Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
3Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
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Kai Yao
5Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China
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Wenli Cai
6Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
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Zhongqiu Xie
2Department of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA
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Fujun Qin
2Department of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA
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Hui Li
2Department of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA
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Xu Chen
1Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
3Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
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Kaiwen Li
1Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
3Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
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  • For correspondence: huangh9{at}mail.sysu.edu.cn likw6{at}mail.sysu.edu.cn
Hai Huang
1Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
3Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
7Department of Urology, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People’s Hospital, Qingyuan 511518, China
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  • For correspondence: huangh9{at}mail.sysu.edu.cn likw6{at}mail.sysu.edu.cn
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Cancer Biology & Medicine: 19 (8)
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Loss of NEIL3 activates radiotherapy resistance in the progression of prostate cancer
Qiong Wang, Zean Li, Jin Yang, Shirong Peng, Qianghua Zhou, Kai Yao, Wenli Cai, Zhongqiu Xie, Fujun Qin, Hui Li, Xu Chen, Kaiwen Li, Hai Huang
Cancer Biology & Medicine Aug 2022, 19 (8) 1193-1210; DOI: 10.20892/j.issn.2095-3941.2020.0550

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Loss of NEIL3 activates radiotherapy resistance in the progression of prostate cancer
Qiong Wang, Zean Li, Jin Yang, Shirong Peng, Qianghua Zhou, Kai Yao, Wenli Cai, Zhongqiu Xie, Fujun Qin, Hui Li, Xu Chen, Kaiwen Li, Hai Huang
Cancer Biology & Medicine Aug 2022, 19 (8) 1193-1210; DOI: 10.20892/j.issn.2095-3941.2020.0550
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Keywords

  • CRPC
  • NEIL3
  • NEPC
  • Prostate cancer
  • radiotherapy resistance

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