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History
- Received February 1, 2022
- Accepted May 5, 2022
- Published online July 27, 2022.
Copyright & Usage
Copyright: © 2022, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Author Information
- 1The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
- 2Department of Oral Maxillofacial-Head Neck Oncology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
- Correspondence to: Lu Zhang and Zhijun Sun, E-mail: luzhang2012{at}whu.edu.cn and sunzj{at}whu.edu.cn
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Eliciting pyroptosis to fuel cancer immunotherapy: mechanisms and strategies
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- Abstract
- Introduction
- Mechanism of pyroptosis
- Pyroptosis of cancer cells regulates the tumor immune microenvironment
- Pyroptosis and cancer therapy
- Potential for synergy between immune checkpoint blockade and localized pyroptosis-inducing therapies
- Conclusions and perspectives
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- Conflict of interest statement
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