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Research ArticleOriginal Article

Somatic copy number alterations are predictive of progression-free survival in patients with lung adenocarcinoma undergoing radiotherapy

Fan Kou, Lei Wu, Yan Guo, Bailu Zhang, Baihui Li, Ziqi Huang, Xiubao Ren and Lili Yang
Cancer Biology & Medicine May 2022, 19 (5) 685-695; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0728
Fan Kou
1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, China
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Lei Wu
1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, China
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Yan Guo
1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, China
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Bailu Zhang
1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, China
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Baihui Li
1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, China
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Ziqi Huang
1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, China
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Xiubao Ren
1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, China
2Department of Biotherapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China
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  • For correspondence: yanglili{at}tjmuch.com renxiubao{at}tjmuch.com
Lili Yang
1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, China
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  • ORCID record for Lili Yang
  • For correspondence: yanglili{at}tjmuch.com renxiubao{at}tjmuch.com
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Article Information

vol. 19 no. 5 685-695
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2020.0728
PubMed 
34448554

Published By 
Cancer Biology & Medicine
History 
  • Received November 26, 2020
  • Accepted May 19, 2021
  • Published online June 24, 2022.

Copyright & Usage 
Copyright: © 2022, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Author Information

  1. Fan Kou1,*,
  2. Lei Wu1,*,
  3. Yan Guo1,
  4. Bailu Zhang1,
  5. Baihui Li1,
  6. Ziqi Huang1,
  7. Xiubao Ren1,2⇑ and
  8. Lili Yang1⇑
  1. 1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, China
  2. 2Department of Biotherapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China
  1. Correspondence to: Lili Yang and Xiubao Ren, E-mail: yanglili{at}tjmuch.com and renxiubao{at}tjmuch.com
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Cancer Biology & Medicine: 19 (5)
Cancer Biology & Medicine
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Somatic copy number alterations are predictive of progression-free survival in patients with lung adenocarcinoma undergoing radiotherapy
Fan Kou, Lei Wu, Yan Guo, Bailu Zhang, Baihui Li, Ziqi Huang, Xiubao Ren, Lili Yang
Cancer Biology & Medicine May 2022, 19 (5) 685-695; DOI: 10.20892/j.issn.2095-3941.2020.0728

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Somatic copy number alterations are predictive of progression-free survival in patients with lung adenocarcinoma undergoing radiotherapy
Fan Kou, Lei Wu, Yan Guo, Bailu Zhang, Baihui Li, Ziqi Huang, Xiubao Ren, Lili Yang
Cancer Biology & Medicine May 2022, 19 (5) 685-695; DOI: 10.20892/j.issn.2095-3941.2020.0728
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Keywords

  • SCNA
  • radiotherapy
  • Lung cancer
  • progression-free survival
  • immune infiltration

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