Review ArticleReview
Heterogeneity of neutrophils in cancer: one size does not fit all
Song Chen, Qingyu Zhang, Lisha Lu, Chunhui Xu, Jiajia Li, Jiali Zha, Fengxia Ma, Hongbo R. Luo and Alan Y. Hsu
Cancer Biology & Medicine December 2022, 19 (12) 1629-1648; DOI: https://doi.org/10.20892/j.issn.2095-3941.2022.0426
Song Chen
1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China
Qingyu Zhang
1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China
Lisha Lu
1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China
Chunhui Xu
1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China
Jiajia Li
1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China
Jiali Zha
2Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
Fengxia Ma
1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China
Hongbo R. Luo
2Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
3Department of Laboratory Medicine, The Stem Cell Program, Boston Children’s Hospital, Boston, MA 02115, USA
4Dana-Farber/Harvard Cancer Center, Boston, MA 02115, USA
Alan Y. Hsu
2Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
3Department of Laboratory Medicine, The Stem Cell Program, Boston Children’s Hospital, Boston, MA 02115, USA
4Dana-Farber/Harvard Cancer Center, Boston, MA 02115, USA
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In this issue
Heterogeneity of neutrophils in cancer: one size does not fit all
Song Chen, Qingyu Zhang, Lisha Lu, Chunhui Xu, Jiajia Li, Jiali Zha, Fengxia Ma, Hongbo R. Luo, Alan Y. Hsu
Cancer Biology & Medicine Dec 2022, 19 (12) 1629-1648; DOI: 10.20892/j.issn.2095-3941.2022.0426
Jump to section
- Article
- Abstract
- Introduction
- Neutrophil differentiation, mobilization, and death
- Neutrophil recruitment in tissues and tumors
- Neutrophil heterogeneity
- Pro-tumoral neutrophil functions
- Neutrophil antitumoral functions
- Neutrophils in tumor metastasis
- Conclusion
- Grant support
- Conflict of interest statement
- Author contributions
- References
- Figures & Data
- References
- Info & Metrics
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