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Research ArticleOriginal Article

Radiotherapy delays malignant transformation and prolongs survival in patients with IDH-mutant gliomas

Yanwei Liu, Huiyuan Chen, Guanzhang Li, Jing Zhang, Kun Yao, Chenxing Wu, Shouwei Li and Xiaoguang Qiu
Cancer Biology & Medicine October 2022, 19 (10) 1477-1486; DOI: https://doi.org/10.20892/j.issn.2095-3941.2022.0472
Yanwei Liu
1Department of Radiation Oncology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
2National Clinical Research Center for Neurological Diseases, Beijing 100070, China
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Huiyuan Chen
2National Clinical Research Center for Neurological Diseases, Beijing 100070, China
3Department of Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100070, China
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Guanzhang Li
2National Clinical Research Center for Neurological Diseases, Beijing 100070, China
4Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
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Jing Zhang
1Department of Radiation Oncology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
2National Clinical Research Center for Neurological Diseases, Beijing 100070, China
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Kun Yao
5Department of Neuropathology, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China
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Chenxing Wu
6Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China
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Shouwei Li
6Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China
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Xiaoguang Qiu
1Department of Radiation Oncology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
2National Clinical Research Center for Neurological Diseases, Beijing 100070, China
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  • ORCID record for Xiaoguang Qiu
  • For correspondence: [email protected]
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Radiotherapy delays malignant transformation and prolongs survival in patients with IDH-mutant gliomas
Yanwei Liu, Huiyuan Chen, Guanzhang Li, Jing Zhang, Kun Yao, Chenxing Wu, Shouwei Li, Xiaoguang Qiu
Cancer Biology & Medicine Oct 2022, 19 (10) 1477-1486; DOI: 10.20892/j.issn.2095-3941.2022.0472

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Radiotherapy delays malignant transformation and prolongs survival in patients with IDH-mutant gliomas
Yanwei Liu, Huiyuan Chen, Guanzhang Li, Jing Zhang, Kun Yao, Chenxing Wu, Shouwei Li, Xiaoguang Qiu
Cancer Biology & Medicine Oct 2022, 19 (10) 1477-1486; DOI: 10.20892/j.issn.2095-3941.2022.0472
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Keywords

  • Lower-grade gliomas
  • IDH mutation
  • radiotherapy
  • malignant transformation
  • survival

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