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Research ArticleOriginal Article

Radiotherapy delays malignant transformation and prolongs survival in patients with IDH-mutant gliomas

Yanwei Liu, Huiyuan Chen, Guanzhang Li, Jing Zhang, Kun Yao, Chenxing Wu, Shouwei Li and Xiaoguang Qiu
Cancer Biology & Medicine October 2022, 19 (10) 1477-1486; DOI: https://doi.org/10.20892/j.issn.2095-3941.2022.0472
Yanwei Liu
1Department of Radiation Oncology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
2National Clinical Research Center for Neurological Diseases, Beijing 100070, China
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Huiyuan Chen
2National Clinical Research Center for Neurological Diseases, Beijing 100070, China
3Department of Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100070, China
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Guanzhang Li
2National Clinical Research Center for Neurological Diseases, Beijing 100070, China
4Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
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Jing Zhang
1Department of Radiation Oncology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
2National Clinical Research Center for Neurological Diseases, Beijing 100070, China
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Kun Yao
5Department of Neuropathology, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China
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Chenxing Wu
6Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China
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Shouwei Li
6Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China
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Xiaoguang Qiu
1Department of Radiation Oncology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
2National Clinical Research Center for Neurological Diseases, Beijing 100070, China
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  • ORCID record for Xiaoguang Qiu
  • For correspondence: [email protected]
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Article Information

vol. 19 no. 10 1477-1486
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2022.0472

Published By 
Cancer Biology & Medicine
History 
  • Received August 6, 2022
  • Accepted September 20, 2022
  • Published online November 3, 2022.

Copyright & Usage 
Copyright: © 2022, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Author Information

  1. Yanwei Liu1,2,*,
  2. Huiyuan Chen2,3,*,
  3. Guanzhang Li2,4,
  4. Jing Zhang1,2,
  5. Kun Yao5,
  6. Chenxing Wu6,
  7. Shouwei Li6 and
  8. Xiaoguang Qiu1,2⇑
  1. 1Department of Radiation Oncology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
  2. 2National Clinical Research Center for Neurological Diseases, Beijing 100070, China
  3. 3Department of Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100070, China
  4. 4Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
  5. 5Department of Neuropathology, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China
  6. 6Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China
  1. Correspondence to: Xiaoguang Qiu E-mail: qiuxiaoguang{at}bjtth.org
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Cancer Biology & Medicine: 19 (10)
Cancer Biology & Medicine
Vol. 19, Issue 10
15 Oct 2022
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Radiotherapy delays malignant transformation and prolongs survival in patients with IDH-mutant gliomas
Yanwei Liu, Huiyuan Chen, Guanzhang Li, Jing Zhang, Kun Yao, Chenxing Wu, Shouwei Li, Xiaoguang Qiu
Cancer Biology & Medicine Oct 2022, 19 (10) 1477-1486; DOI: 10.20892/j.issn.2095-3941.2022.0472

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Radiotherapy delays malignant transformation and prolongs survival in patients with IDH-mutant gliomas
Yanwei Liu, Huiyuan Chen, Guanzhang Li, Jing Zhang, Kun Yao, Chenxing Wu, Shouwei Li, Xiaoguang Qiu
Cancer Biology & Medicine Oct 2022, 19 (10) 1477-1486; DOI: 10.20892/j.issn.2095-3941.2022.0472
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Keywords

  • Lower-grade gliomas
  • IDH mutation
  • radiotherapy
  • malignant transformation
  • survival

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