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Research ArticleOriginal Article

The combination of chidamide with the CHOEP regimen in previously untreated patients with peripheral T-cell lymphoma: a prospective, multicenter, single arm, phase 1b/2 study

Wei Zhang, Liping Su, Lihong Liu, Yuhuan Gao, Quanshun Wang, Hang Su, Yuhuan Song, Huilai Zhang, Jing Shen, Hongmei Jing, Shuye Wang, Xinan Cen, Hui Liu, Aichun Liu, Zengjun Li, Jianmin Luo, Jianxia He, Jingwen Wang, O. A. O’Connor and Daobin Zhou
Cancer Biology & Medicine August 2021, 18 (3) 841-848; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0413
Wei Zhang
1Department of Hematology, Peking Union Medical College Hospital, Beijing 100730, China
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Liping Su
2Department of Hematology, Shanxi Provincial Cancer Hospital, Taiyuan 030013, China
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Lihong Liu
3Department of Hematology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China
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Yuhuan Gao
3Department of Hematology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China
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Quanshun Wang
4Department of Hematology, Chinese PLA General Hospital, Beijing 100039, China
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Hang Su
5Department of Lymphoma, the 307 Hospital of PLA, Beijing 100071, China
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Yuhuan Song
6Department of Lymphoma, Peking University Cancer Hospital and Institute, Beijing 100142, China
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Huilai Zhang
7Department of Lymphoma, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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Jing Shen
8Department of Hematology, Beijing Friendship Hospital, Beijing 100050, China
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Hongmei Jing
9Department of Hematology, Peking University Third Hospital, Beijing 100191, China
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Shuye Wang
10Department of Hematology, the First Affiliated Hospital of Harbin Medical University, Harbin 150081, China
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Xinan Cen
11Department of Hematology, Peking University First Hospital, Beijing 100034, China
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Hui Liu
12Department of Hematology, Beijing Hospital, Beijing 100730, China
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Aichun Liu
13Department of Lymphoma, Harbin Medical University Cancer Hospital, Harbin 150081, China
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Zengjun Li
14Lymphoma Diagnosis and Treatment Center, Institute of Hematology and Blood Diseases Hospital, Tianjin 300052, China
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Jianmin Luo
15Department of Hematology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
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Jianxia He
16Department of Hematology, Shanxi Provincial People’s Hospital, Taiyuan 030012, China
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Jingwen Wang
17Department of Hematology, Beijing Tongren Hospital, Beijing 100730, China
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O. A. O’Connor
18Columbia University Medical Center, New York 10032-3784, NY, USA
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Daobin Zhou
1Department of Hematology, Peking Union Medical College Hospital, Beijing 100730, China
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Cancer Biology and Medicine: 18 (3)
Cancer Biology & Medicine
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The combination of chidamide with the CHOEP regimen in previously untreated patients with peripheral T-cell lymphoma: a prospective, multicenter, single arm, phase 1b/2 study
Wei Zhang, Liping Su, Lihong Liu, Yuhuan Gao, Quanshun Wang, Hang Su, Yuhuan Song, Huilai Zhang, Jing Shen, Hongmei Jing, Shuye Wang, Xinan Cen, Hui Liu, Aichun Liu, Zengjun Li, Jianmin Luo, Jianxia He, Jingwen Wang, O. A. O’Connor, Daobin Zhou
Cancer Biology & Medicine Aug 2021, 18 (3) 841-848; DOI: 10.20892/j.issn.2095-3941.2020.0413

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The combination of chidamide with the CHOEP regimen in previously untreated patients with peripheral T-cell lymphoma: a prospective, multicenter, single arm, phase 1b/2 study
Wei Zhang, Liping Su, Lihong Liu, Yuhuan Gao, Quanshun Wang, Hang Su, Yuhuan Song, Huilai Zhang, Jing Shen, Hongmei Jing, Shuye Wang, Xinan Cen, Hui Liu, Aichun Liu, Zengjun Li, Jianmin Luo, Jianxia He, Jingwen Wang, O. A. O’Connor, Daobin Zhou
Cancer Biology & Medicine Aug 2021, 18 (3) 841-848; DOI: 10.20892/j.issn.2095-3941.2020.0413
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Keywords

  • Peripheral T-cell lymphoma
  • chidamide
  • histone deacetylase inhibitor
  • epigenetic

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