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Research ArticleOriginal Article

Equivalent efficacy study of QL1101 and bevacizumab on untreated advanced non-squamous non-small cell lung cancer patients: a phase 3 randomized, double-blind clinical trial

Tianqing Chu, Jun Lu, Minghong Bi, Helong Zhang, Wu Zhuang, Yan Yu, Jianhua Shi, Zhendong Chen, Xiaochun Zhang, Qisen Guo, Quan Liu, Huijuan Wu, Jian Fang, Yi Hu, Xiuwen Wang, Cuicui Han, Kai Li and Baohui Han
Cancer Biology & Medicine August 2021, 18 (3) 816-824; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0212
Tianqing Chu
1Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China
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Jun Lu
1Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China
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Minghong Bi
2Department of Oncology, The First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, China
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Helong Zhang
3Department of Oncology, Tangdu Hospital, Air Force Medical University of PLA, Xi’an 710038, China
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Wu Zhuang
4Department of Medical Thoracic Oncology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou 350014, China
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Yan Yu
5Department of Oncology, Harbin Medical University Cancer Hospital, Harbin 150081, China
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Jianhua Shi
6Department of Oncology, Linyi Cancer Hospital, Linyi 276000, China
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Zhendong Chen
7Department of Oncology, The Second Hospital of Anhui Medical University, Hefei 230601, China
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Xiaochun Zhang
8Department of Oncology, The Affiliated Hospital of Qingdao University, Qingdao 266071, China
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Qisen Guo
9Department of Internal Medicine, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China
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Quan Liu
10Department of Oncology, Affiliated Hospital of Jiang Nan University, Wuxi 214122, China
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Huijuan Wu
11Department of Internal Medicine, Henan Province Tumor Hospital, Zhengzhou University, Zhengzhou 450008, China
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Jian Fang
12Department of Thoracic Oncology II, Peking University Cancer Hospital and Institute, Beijing 100142, China
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Yi Hu
13Department of Oncology, Chinese PLA General Hospital, Beijing 100039, China
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Xiuwen Wang
14Department of Oncology, Qilu Hospital of Shandong University, Jinan 250012, China
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Cuicui Han
15Department of Clinical Research Centre, Qilu Pharmaceutical Co., Ltd, Jinan 250101, China
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Kai Li
16Department of Thoracic Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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  • For correspondence: 18930858216{at}163.com likai_fnk{at}163.com
Baohui Han
1Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China
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  • For correspondence: 18930858216{at}163.com likai_fnk{at}163.com
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Article Information

vol. 18 no. 3 816-824
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2020.0212

Published By 
Cancer Biology & Medicine
History 
  • Received June 6, 2020
  • Accepted August 14, 2020
  • Published online August 1, 2021.

Copyright & Usage 
Copyright: © 2021, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Author Information

  1. Tianqing Chu1,*,
  2. Jun Lu1,*,
  3. Minghong Bi2,
  4. Helong Zhang3,
  5. Wu Zhuang4,
  6. Yan Yu5,
  7. Jianhua Shi6,
  8. Zhendong Chen7,
  9. Xiaochun Zhang8,
  10. Qisen Guo9,
  11. Quan Liu10,
  12. Huijuan Wu11,
  13. Jian Fang12,
  14. Yi Hu13,
  15. Xiuwen Wang14,
  16. Cuicui Han15,
  17. Kai Li16⇑ and
  18. Baohui Han1⇑
  1. 1Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China
  2. 2Department of Oncology, The First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, China
  3. 3Department of Oncology, Tangdu Hospital, Air Force Medical University of PLA, Xi’an 710038, China
  4. 4Department of Medical Thoracic Oncology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou 350014, China
  5. 5Department of Oncology, Harbin Medical University Cancer Hospital, Harbin 150081, China
  6. 6Department of Oncology, Linyi Cancer Hospital, Linyi 276000, China
  7. 7Department of Oncology, The Second Hospital of Anhui Medical University, Hefei 230601, China
  8. 8Department of Oncology, The Affiliated Hospital of Qingdao University, Qingdao 266071, China
  9. 9Department of Internal Medicine, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China
  10. 10Department of Oncology, Affiliated Hospital of Jiang Nan University, Wuxi 214122, China
  11. 11Department of Internal Medicine, Henan Province Tumor Hospital, Zhengzhou University, Zhengzhou 450008, China
  12. 12Department of Thoracic Oncology II, Peking University Cancer Hospital and Institute, Beijing 100142, China
  13. 13Department of Oncology, Chinese PLA General Hospital, Beijing 100039, China
  14. 14Department of Oncology, Qilu Hospital of Shandong University, Jinan 250012, China
  15. 15Department of Clinical Research Centre, Qilu Pharmaceutical Co., Ltd, Jinan 250101, China
  16. 16Department of Thoracic Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
  1. Correspondence to: Baohui Han and Kai Li, E-mail: 18930858216{at}163.com and likai_fnk{at}163.com
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Cancer Biology and Medicine: 18 (3)
Cancer Biology & Medicine
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Equivalent efficacy study of QL1101 and bevacizumab on untreated advanced non-squamous non-small cell lung cancer patients: a phase 3 randomized, double-blind clinical trial
Tianqing Chu, Jun Lu, Minghong Bi, Helong Zhang, Wu Zhuang, Yan Yu, Jianhua Shi, Zhendong Chen, Xiaochun Zhang, Qisen Guo, Quan Liu, Huijuan Wu, Jian Fang, Yi Hu, Xiuwen Wang, Cuicui Han, Kai Li, Baohui Han
Cancer Biology & Medicine Aug 2021, 18 (3) 816-824; DOI: 10.20892/j.issn.2095-3941.2020.0212

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Equivalent efficacy study of QL1101 and bevacizumab on untreated advanced non-squamous non-small cell lung cancer patients: a phase 3 randomized, double-blind clinical trial
Tianqing Chu, Jun Lu, Minghong Bi, Helong Zhang, Wu Zhuang, Yan Yu, Jianhua Shi, Zhendong Chen, Xiaochun Zhang, Qisen Guo, Quan Liu, Huijuan Wu, Jian Fang, Yi Hu, Xiuwen Wang, Cuicui Han, Kai Li, Baohui Han
Cancer Biology & Medicine Aug 2021, 18 (3) 816-824; DOI: 10.20892/j.issn.2095-3941.2020.0212
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