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Research ArticleOriginal Article

LncRNA DPP10-AS1 promotes malignant processes through epigenetically activating its cognate gene DPP10 and predicts poor prognosis in lung cancer patients

Haihua Tian, Jinchang Pan, Shuai Fang, Chengwei Zhou, Hui Tian, Jinxian He, Weiyu Shen, Xiaodan Meng, Xiaofeng Jin and Zhaohui Gong
Cancer Biology & Medicine August 2021, 18 (3) 675-692; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0136
Haihua Tian
1Department of Biochemistry and Molecular Biology, Ningbo University School of Medicine, Ningbo 315211, China
2Zhejiang Province Key Laboratory of Pathophysiology, Ningbo University School of Medicine, Ningbo 315211, China
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Jinchang Pan
1Department of Biochemistry and Molecular Biology, Ningbo University School of Medicine, Ningbo 315211, China
2Zhejiang Province Key Laboratory of Pathophysiology, Ningbo University School of Medicine, Ningbo 315211, China
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Shuai Fang
1Department of Biochemistry and Molecular Biology, Ningbo University School of Medicine, Ningbo 315211, China
2Zhejiang Province Key Laboratory of Pathophysiology, Ningbo University School of Medicine, Ningbo 315211, China
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Chengwei Zhou
1Department of Biochemistry and Molecular Biology, Ningbo University School of Medicine, Ningbo 315211, China
3Department of Thoracic Surgery, The Affiliated Hospital of Ningbo University School of Medicine, Ningbo 315020, China
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Hui Tian
4Department of Thoracic Surgery, The Affiliated Lihuili Hospital of Ningbo University, Ningbo 315048, China
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Jinxian He
4Department of Thoracic Surgery, The Affiliated Lihuili Hospital of Ningbo University, Ningbo 315048, China
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Weiyu Shen
4Department of Thoracic Surgery, The Affiliated Lihuili Hospital of Ningbo University, Ningbo 315048, China
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Xiaodan Meng
1Department of Biochemistry and Molecular Biology, Ningbo University School of Medicine, Ningbo 315211, China
2Zhejiang Province Key Laboratory of Pathophysiology, Ningbo University School of Medicine, Ningbo 315211, China
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Xiaofeng Jin
1Department of Biochemistry and Molecular Biology, Ningbo University School of Medicine, Ningbo 315211, China
2Zhejiang Province Key Laboratory of Pathophysiology, Ningbo University School of Medicine, Ningbo 315211, China
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Zhaohui Gong
1Department of Biochemistry and Molecular Biology, Ningbo University School of Medicine, Ningbo 315211, China
2Zhejiang Province Key Laboratory of Pathophysiology, Ningbo University School of Medicine, Ningbo 315211, China
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  • ORCID record for Zhaohui Gong
  • For correspondence: zhaohui{at}ncri.org.cn
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LncRNA DPP10-AS1 promotes malignant processes through epigenetically activating its cognate gene DPP10 and predicts poor prognosis in lung cancer patients
Haihua Tian, Jinchang Pan, Shuai Fang, Chengwei Zhou, Hui Tian, Jinxian He, Weiyu Shen, Xiaodan Meng, Xiaofeng Jin, Zhaohui Gong
Cancer Biology & Medicine Aug 2021, 18 (3) 675-692; DOI: 10.20892/j.issn.2095-3941.2020.0136

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LncRNA DPP10-AS1 promotes malignant processes through epigenetically activating its cognate gene DPP10 and predicts poor prognosis in lung cancer patients
Haihua Tian, Jinchang Pan, Shuai Fang, Chengwei Zhou, Hui Tian, Jinxian He, Weiyu Shen, Xiaodan Meng, Xiaofeng Jin, Zhaohui Gong
Cancer Biology & Medicine Aug 2021, 18 (3) 675-692; DOI: 10.20892/j.issn.2095-3941.2020.0136
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Keywords

  • Antisense long noncoding RNA
  • DPP10-AS1
  • hypomethylation
  • malignant process
  • Lung cancer

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