Table of Contents

Original Article

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  FGFR/RACK1 interacts with MDM2, promotes P53 degradation, and inhibits cell senescence in lung squamous cell carcinoma

  Tao Chen, Fei Wang, Shupei Wei, Yingjie Nie, Xiaotao Zheng, Yu Deng, Xubin Zhu, Yuezhen Deng, Nanshan Zhong and Chengzhi Zhou

  Cancer Biology & Medicine August 2021, 18 (3) 665-674; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0389
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  LncRNA DPP10-AS1 promotes malignant processes through epigenetically activating its cognate gene DPP10 and predicts poor prognosis in lung cancer patients

  Haihua Tian, Jinchang Pan, Shuai Fang, Chengwei Zhou, Hui Tian, Jinxian He, Weiyu Shen, Xiaodan Meng, Xiaofeng Jin and Zhaohui Gong

  Cancer Biology & Medicine August 2021, 18 (3) 675-692; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0136
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  Heat shock protein 90 promotes RNA helicase DDX5 accumulation and exacerbates hepatocellular carcinoma by inhibiting autophagy

  Ting Zhang, Xinrui Yang, Wanping Xu, Jing Wang, Dawei Wu, Zhixian Hong, Shengxian Yuan, Zhen Zeng, Xiaodong Jia, Shanshan Lu, Rifaat Safadi, Sen Han, Zhihong Yang, Leonard M. Neckers, Suthat Liangpunsakul, Weiping Zhou and Yinying Lu

  Cancer Biology & Medicine August 2021, 18 (3) 693-704; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0262
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  NEDD9 promotes cancer stemness by recruiting myeloid-derived suppressor cells via CXCL8 in esophageal squamous cell carcinoma

  Dongli Yue, Shasha Liu, Tengfei Zhang, Yong Wang, Guohui Qin, Xinfeng Chen, Huanyu Zhang, Dong Wang, Lan Huang, Feng Wang, Liping Wang, Song Zhao and Yi Zhang

  Cancer Biology & Medicine August 2021, 18 (3) 705-720; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0290
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  Complement C3a activates osteoclasts by regulating the PI3K/PDK1/SGK3 pathway in patients with multiple myeloma

  Fengjuan Jiang, Hui Liu, Fengping Peng, Zhaoyun Liu, Kai Ding, Jia Song, Lijuan Li, Jin Chen, Qing Shao, Siyang Yan, Kim De Veirman, Karin Vanderkerken and Rong Fu

  Cancer Biology & Medicine August 2021, 18 (3) 721-733; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0430
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  A novel recurrence-associated metabolic prognostic model for risk stratification and therapeutic response prediction in patients with stage I lung adenocarcinoma

  Chengming Liu, Sihui Wang, Sufei Zheng, Xinfeng Wang, Jianbin Huang, Yuanyuan Lei, Shuangshuang Mao, Xiaoli Feng, Nan Sun and Jie He

  Cancer Biology & Medicine August 2021, 18 (3) 734-749; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0397
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  Raltitrexed as a synergistic hyperthermia chemotherapy drug screened in patient-derived colorectal cancer organoids

  Lisi Zeng, Quanxing Liao, Haoran Zhao, Shengwei Jiang, Xianzi Yang, Hongsheng Tang, Qingjun He, Xiansheng Yang, Shuxian Fang, Jinfu He, Weiwen Cui, Laiqiang Huang, Shaohua Ma and Shuzhong Cui

  Cancer Biology & Medicine August 2021, 18 (3) 750-762; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0566
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  Development and validation of a risk model for noninvasive detection of cancer in oral potentially malignant disorders using DNA image cytometry

  Chenxi Li, Yongmei Zhou, Yiwen Deng, Xuemin Shen, Linjun Shi and Wei Liu

  Cancer Biology & Medicine August 2021, 18 (3) 763-771; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0531
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  VHH212 nanobody targeting the hypoxia-inducible factor 1α suppresses angiogenesis and potentiates gemcitabine therapy in pancreatic cancer in vivo

  Guangbo Kang, Min Hu, He Ren, Jiewen Wang, Xin Cheng, Ruowei Li, Bo Yuan, Yasmine Balan, Zixuan Bai and He Huang

  Cancer Biology & Medicine August 2021, 18 (3) 772-787; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0568
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  CD44v8-10 is a marker for malignant traits and a potential driver of bone metastasis in a subpopulation of prostate cancer cells

  Rosaria A. Fontanella, Silvia Sideri, Chiara Di Stefano, Angiolina Catizone, Silvia Di Agostino, Daniela F. Angelini, Gisella Guerrera, Luca Battistini, Giulia Battafarano, Andrea Del Fattore, Antonio Francesco Campese, Fabrizio Padula, Paola De Cesaris, Antonio Filippini and Anna Riccioli

  Cancer Biology & Medicine August 2021, 18 (3) 788-807; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0495
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  Typing of biliary tumor thrombus influences the prognoses of patients with hepatocellular carcinoma

  Juxian Sun, Jiayi Wu, Chang Liu, Jie Shi, Yonggang Wei, Jianyin Zhou, Zhibo Zhang, Wan Yee Lau, Maolin Yan and Shuqun Cheng

  Cancer Biology & Medicine August 2021, 18 (3) 808-815; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0202
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  Equivalent efficacy study of QL1101 and bevacizumab on untreated advanced non-squamous non-small cell lung cancer patients: a phase 3 randomized, double-blind clinical trial

  Tianqing Chu, Jun Lu, Minghong Bi, Helong Zhang, Wu Zhuang, Yan Yu, Jianhua Shi, Zhendong Chen, Xiaochun Zhang, Qisen Guo, Quan Liu, Huijuan Wu, Jian Fang, Yi Hu, Xiuwen Wang, Cuicui Han, Kai Li and Baohui Han

  Cancer Biology & Medicine August 2021, 18 (3) 816-824; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0212
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  Identification of optimal contemporary antiemetic prophylaxis for doxorubicin-cyclophosphamide chemotherapy in Chinese cancer patients: post-hoc analysis of 3 prospective studies

  Winnie Yeo, Leung Li, Thomas KH Lau, Kwai T Lai, Vicky TC Chan, Kwan H Wong, Christopher CH Yip, Elizabeth Pang, Maggie Cheung, Vivian Chan, Carol CH Kwok, Joyce JS Suen and Frankie KF Mo

  Cancer Biology & Medicine August 2021, 18 (3) 825-832; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0241
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  Modified R-CODOX-M/IVAC chemotherapy regimens in Chinese patients with untreated sporadic Burkitt lymphoma

  Meiting Chen, Zhao Wang, Xiaojie Fang, Yuyi Yao, Quanguang Ren, Zegeng Chen, Ying Tian, Fei Pan, Xiaoqian Li, Zhiming Li, Qingqing Cai, He Huang and Tongyu Lin

  Cancer Biology & Medicine August 2021, 18 (3) 833-840; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0314
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  The combination of chidamide with the CHOEP regimen in previously untreated patients with peripheral T-cell lymphoma: a prospective, multicenter, single arm, phase 1b/2 study

  Wei Zhang, Liping Su, Lihong Liu, Yuhuan Gao, Quanshun Wang, Hang Su, Yuhuan Song, Huilai Zhang, Jing Shen, Hongmei Jing, Shuye Wang, Xinan Cen, Hui Liu, Aichun Liu, Zengjun Li, Jianmin Luo, Jianxia He, Jingwen Wang, O. A. O’Connor and Daobin Zhou

  Cancer Biology & Medicine August 2021, 18 (3) 841-848; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0413
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  Transcription factor-based gene therapy to treat glioblastoma through direct neuronal conversion

  Xin Wang, Zifei Pei, Aasma Hossain, Yuting Bai and Gong Chen

  Cancer Biology & Medicine August 2021, 18 (3) 860-874; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0499
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  Phase II study of apatinib in combination with oral vinorelbine in heavily pretreated HER2-negative metastatic breast cancer and clinical implications of monitoring ctDNA

  Anjie Zhu, Peng Yuan, Nanlin Hu, Mingzhou Li, Wenmiao Wang, Xue Wang, Jian Yue, Jiayu Wang, Yang Luo, Fei Ma, Pin Zhang, Qing Li, Binghe Xu, Shanbo Cao, Giuseppe Lippi, Yoichi Naito, Mohammed A. Osman, Gustavo N. Marta, Gianluca Franceschini and Armando Orlandi

  Cancer Biology & Medicine August 2021, 18 (3) 875-887; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0418
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  Epstein-Barr virus DNA loads in the peripheral blood cells predict the survival of locoregionally-advanced nasopharyngeal carcinoma patients

  Yongqiao He, Dawei Yang, Ting Zhou, Wenqiong Xue, Jiangbo Zhang, Fangfang Li, Fang Wang, Tongmin Wang, Ziyi Wu, Ying Liao, Meiqi Zheng, Changmi Deng, Danhua Li, Yijing Jia, Leilei Yuan, Wenli Zhang and Weihua Jia

  Cancer Biology & Medicine August 2021, 18 (3) 888-899; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0464
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  Breast cancer incidence and mortality in women in China: temporal trends and projections to 2030

  Shaoyuan Lei, Rongshou Zheng, Siwei Zhang, Ru Chen, Shaoming Wang, Kexin Sun, Hongmei Zeng, Wenqiang Wei and Jie He

  Cancer Biology & Medicine August 2021, 18 (3) 900-909; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0523
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  Efficacy of the new therapeutic approach in curing malignant neoplasms on the model of human glioblastoma

  Evgeniya V. Dolgova, Oleg M. Andrushkevich, Polina E. Kisaretova, Anastasia S. Proskurina, Genrikh S. Ritter, Tatyana D. Dubatolova, Margarita V. Romanenko, Oleg S. Taranov, Yaroslav R. Efremov, Evgeniy L. Zavyalov, Alexandr V. Romaschenko, Sergey V. Mishinov, Svetlana S. Kirikovich, Evgeniy V. Levites, Ekaterina A. Potter, Alexandr A. Ostanin, Elena R. Chernykh, Stanislav Yu. Roshchin, Anatoliy V. Bervitskiy, Galina I. Moysak, Jamil A. Rzaev and Sergey S. Bogachev

  Cancer Biology & Medicine August 2021, 18 (3) 910-930; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0511