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Research ArticleOriginal Article

The relationship between treatment-induced hypertension and efficacy of anlotinib in recurrent or metastatic esophageal squamous cell carcinoma

Yan Song, Juxiang Xiao, Wentao Fang, Ping Lu, Qingxia Fan, Yongqian Shu, Jifeng Feng, Shu Zhang, Yi Ba, Yang Zhao, Ying Liu, Chunmei Bai, Yuxian Bai, Yong Tang, Jie He and Jing Huang
Cancer Biology & Medicine May 2021, 18 (2) 562-568; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0187
Yan Song
1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
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Juxiang Xiao
2Department of Medical Oncology, First Hospital of Xi’an Jiaotong University, Xi’an 710061, China
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Wentao Fang
3Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China
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Ping Lu
4Department of Medical Oncology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, China
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Qingxia Fan
5Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
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Yongqian Shu
6Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
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Jifeng Feng
7Department of Medical Oncology, Jiangsu Cancer Hospital, Nanjing 210009, China
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Shu Zhang
8Department of Medical Oncology, Shandong Cancer Hospital, Jinan 250117, China
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Yi Ba
9Department of Medical Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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Yang Zhao
10Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 210029, China
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Ying Liu
11Department of Medical Oncology, Henan Cancer Hospital, Zhengzhou 450008, China
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Chunmei Bai
12Department of Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China
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Yuxian Bai
13Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin 150086, China
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Yong Tang
14Department of Gastroenterology, Affiliated Tumor Hospital, Xinjiang Medical University, Urumqi 830011, China
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Jie He
15Department of Thoracic Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
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  • ORCID record for Jie He
  • For correspondence: huangjingwg{at}163.com hejie{at}cicams.ac.cn
Jing Huang
1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
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  • For correspondence: huangjingwg{at}163.com hejie{at}cicams.ac.cn
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Article Information

vol. 18 no. 2 562-568
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2020.0187

Published By 
Cancer Biology & Medicine
History 
  • Received April 23, 2020
  • Accepted September 16, 2020
  • Published online May 1, 2021.

Copyright & Usage 
Copyright: © 2021, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Author Information

  1. Yan Song1,
  2. Juxiang Xiao2,
  3. Wentao Fang3,
  4. Ping Lu4,
  5. Qingxia Fan5,
  6. Yongqian Shu6,
  7. Jifeng Feng7,
  8. Shu Zhang8,
  9. Yi Ba9,
  10. Yang Zhao10,
  11. Ying Liu11,
  12. Chunmei Bai12,
  13. Yuxian Bai13,
  14. Yong Tang14,
  15. Jie He15⇑ and
  16. Jing Huang1⇑
  1. 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  2. 2Department of Medical Oncology, First Hospital of Xi’an Jiaotong University, Xi’an 710061, China
  3. 3Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China
  4. 4Department of Medical Oncology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, China
  5. 5Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
  6. 6Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
  7. 7Department of Medical Oncology, Jiangsu Cancer Hospital, Nanjing 210009, China
  8. 8Department of Medical Oncology, Shandong Cancer Hospital, Jinan 250117, China
  9. 9Department of Medical Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
  10. 10Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 210029, China
  11. 11Department of Medical Oncology, Henan Cancer Hospital, Zhengzhou 450008, China
  12. 12Department of Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China
  13. 13Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin 150086, China
  14. 14Department of Gastroenterology, Affiliated Tumor Hospital, Xinjiang Medical University, Urumqi 830011, China
  15. 15Department of Thoracic Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  1. Correspondence to: Jing Huang and Jie He, E-mail: huangjingwg{at}163.com and hejie{at}cicams.ac.cn
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Cancer Biology and Medicine: 18 (2)
Cancer Biology & Medicine
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The relationship between treatment-induced hypertension and efficacy of anlotinib in recurrent or metastatic esophageal squamous cell carcinoma
Yan Song, Juxiang Xiao, Wentao Fang, Ping Lu, Qingxia Fan, Yongqian Shu, Jifeng Feng, Shu Zhang, Yi Ba, Yang Zhao, Ying Liu, Chunmei Bai, Yuxian Bai, Yong Tang, Jie He, Jing Huang
Cancer Biology & Medicine May 2021, 18 (2) 562-568; DOI: 10.20892/j.issn.2095-3941.2020.0187

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The relationship between treatment-induced hypertension and efficacy of anlotinib in recurrent or metastatic esophageal squamous cell carcinoma
Yan Song, Juxiang Xiao, Wentao Fang, Ping Lu, Qingxia Fan, Yongqian Shu, Jifeng Feng, Shu Zhang, Yi Ba, Yang Zhao, Ying Liu, Chunmei Bai, Yuxian Bai, Yong Tang, Jie He, Jing Huang
Cancer Biology & Medicine May 2021, 18 (2) 562-568; DOI: 10.20892/j.issn.2095-3941.2020.0187
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Keywords

  • Esophageal squamous cell carcinoma (ESCC)
  • anlotinib
  • treatment-induced hypertension
  • prognostic predictor
  • antiangiogenesis

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