Research ArticleOriginal Article

Three-dimensional collagen-based scaffold model to study the microenvironment and drug-resistance mechanisms of oropharyngeal squamous cell carcinomas

Giacomo Miserocchi, Claudia Cocchi, Alessandro De Vita, Chiara Liverani, Chiara Spadazzi, Sebastiano Calpona, Giandomenico Di Menna, Massimo Bassi, Giuseppe Meccariello, Giovanni De Luca, Angelo Campobassi, Maria Maddalena Tumedei, Alberto Bongiovanni, Valentina Fausti, Franco Cotelli, Toni Ibrahim and Laura Mercatali
Cancer Biology & Medicine May 2021, 18 (2) 502-516; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0482

Article Information

vol. 18 no. 2 502-516
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2020.0482
Published By 
Cancer Biology & Medicine
History 
  • Received August 19, 2020
  • Accepted December 15, 2020
  • Published online May 1, 2021.
Copyright & Usage 
Copyright: © 2021, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Author Information

  1. Giacomo Miserocchi1,
  2. Claudia Cocchi1,
  3. Alessandro De Vita1⇑,
  4. Chiara Liverani1,
  5. Chiara Spadazzi1,
  6. Sebastiano Calpona1,
  7. Giandomenico Di Menna1,
  8. Massimo Bassi2,
  9. Giuseppe Meccariello3,
  10. Giovanni De Luca4,
  11. Angelo Campobassi2,
  12. Maria Maddalena Tumedei5,
  13. Alberto Bongiovanni1,
  14. Valentina Fausti1,
  15. Franco Cotelli6,
  16. Toni Ibrahim1 and
  17. Laura Mercatali1
  1. 1Osteoncology and Rare Tumors Center, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola 47014, Italy
  2. 2Maxillofacial Surgery Unit, Bufalini Hospital, Cesena 47521, Italy
  3. 3Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Forlì 47121, Italy
  4. 4Pathology Unit, “Bufalini” Hospital, AUSL Romagna, Cesena 47521, Italy
  5. 5Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola 47014, Italy
  6. 6Department of Biosciences, Università degli Studi di Milano, Milan 20133, Italy
  1. Correspondence to: Alessandro De Vita, E-mail: alessandro.devita{at}irst.emr.it
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