Research ArticleOriginal Article
The cancer-testis gene, MEIOB, sensitizes triple-negative breast cancer to PARP1 inhibitors by inducing homologous recombination deficiency
Yayun Gu, Cheng Wang, Rongxuan Zhu, Jianshui Yang, Wenwen Yuan, Yanhui Zhu, Yan Zhou, Na Qin, Hongbing Shen, Hongxia Ma, Hongxia Wang, Xiaoan Liu and Zhibin Hu
Cancer Biology & Medicine February 2021, 18 (1) 74-87; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0071
Yayun Gu
1State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China
2Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing 211116, China
Cheng Wang
1State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China
2Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing 211116, China
3Department of Bioinformatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing 211166, China
Rongxuan Zhu
4Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China
Jianshui Yang
1State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China
Wenwen Yuan
1State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China
2Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing 211116, China
Yanhui Zhu
5Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing 210029, China
Yan Zhou
1State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China
2Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing 211116, China
Na Qin
1State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China
2Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing 211116, China
Hongbing Shen
1State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China
2Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing 211116, China
Hongxia Ma
1State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China
2Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing 211116, China
Hongxia Wang
4Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China
Xiaoan Liu
5Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing 210029, China
Zhibin Hu
1State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China
2Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing 211116, China
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In this issue
The cancer-testis gene, MEIOB, sensitizes triple-negative breast cancer to PARP1 inhibitors by inducing homologous recombination deficiency
Yayun Gu, Cheng Wang, Rongxuan Zhu, Jianshui Yang, Wenwen Yuan, Yanhui Zhu, Yan Zhou, Na Qin, Hongbing Shen, Hongxia Ma, Hongxia Wang, Xiaoan Liu, Zhibin Hu
Cancer Biology & Medicine Feb 2021, 18 (1) 74-87; DOI: 10.20892/j.issn.2095-3941.2020.0071
The cancer-testis gene, MEIOB, sensitizes triple-negative breast cancer to PARP1 inhibitors by inducing homologous recombination deficiency
Yayun Gu, Cheng Wang, Rongxuan Zhu, Jianshui Yang, Wenwen Yuan, Yanhui Zhu, Yan Zhou, Na Qin, Hongbing Shen, Hongxia Ma, Hongxia Wang, Xiaoan Liu, Zhibin Hu
Cancer Biology & Medicine Feb 2021, 18 (1) 74-87; DOI: 10.20892/j.issn.2095-3941.2020.0071
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