Table of Contents

Original Article

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  The cancer-testis gene, MEIOB, sensitizes triple-negative breast cancer to PARP1 inhibitors by inducing homologous recombination deficiency

  Yayun Gu, Cheng Wang, Rongxuan Zhu, Jianshui Yang, Wenwen Yuan, Yanhui Zhu, Yan Zhou, Na Qin, Hongbing Shen, Hongxia Ma, Hongxia Wang, Xiaoan Liu and Zhibin Hu

  Cancer Biology & Medicine February 2021, 18 (1) 74-87; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0071
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  BYSL contributes to tumor growth by cooperating with the mTORC2 complex in gliomas

  Shangfeng Gao, Zhuang Sha, Junbo Zhou, Yihao Wu, Yunnong Song, Cheng Li, Xuejiao Liu, Tong Zhang and Rutong Yu

  Cancer Biology & Medicine February 2021, 18 (1) 88-104; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0096
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  Oncoprotein HBXIP promotes tumorigenesis through MAPK/ERK pathway activation in non-small cell lung cancer

  Jun Zhang, Bei Sun, Xianhui Ruan, Xiukun Hou, Jingtai Zhi, Xiangrui Meng, Xiangqian Zheng and Ming Gao

  Cancer Biology & Medicine February 2021, 18 (1) 105-119; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0098
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  RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer

  Guosheng Lyu, Peng Su, Xiaohe Hao, Shiming Chen, Shuai Ren, Zixiao Zhao, Yaoqin Gong, Qiao Liu and Changshun Shao

  Cancer Biology & Medicine February 2021, 18 (1) 120-138; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0105
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  VEGFR2 inhibition hampers breast cancer cell proliferation via enhanced mitochondrial biogenesis

  Hao Ni, Min Guo, Xuepei Zhang, Lei Jiang, Shuai Tan, Juan Yuan, HuanhuanL Cui, Yanan Min, Junhao Zhang, Susanne Schlisio, Chunhong Ma, Wangjun Liao, Monica Nister, Chunlin Chen, Shuijie Li and Nailin Li

  Cancer Biology & Medicine February 2021, 18 (1) 139-154; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0151
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  Morphine-3-glucuronide upregulates PD-L1 expression via TLR4 and promotes the immune escape of non-small cell lung cancer

  Kaiyuan Wang, Jian Wang, Ting Liu, Wenwen Yu, Nan Dong, Chen Zhang, Wenbin Xia, Feng Wei, Lili Yang and Xiubao Ren

  Cancer Biology & Medicine February 2021, 18 (1) 155-171; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0442
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  The IL-33/ST2 axis affects tumor growth by regulating mitophagy in macrophages and reprogramming their polarization

  Huadan Xu, Dong Li, Jiaoyan Ma, Yuanxin Zhao, Long Xu, Rui Tian, Yanan Liu, Liankun Sun and Jing Su

  Cancer Biology & Medicine February 2021, 18 (1) 172-183; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0211
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  Patient-derived non-small cell lung cancer xenograft mirrors complex tumor heterogeneity

  Xuanming Chen, Cheng Shen, Zhe Wei, Rui Zhang, Yongsheng Wang, Lili Jiang, Ke Chen, Shuang Qiu, Yuanli Zhang, Ting Zhang, Bin Chen, Yanjun Xu, Qiyi Feng, Jinxing Huang, Zhihui Zhong, Hongxia Li, Guowei Che and Kai Xiao

  Cancer Biology & Medicine February 2021, 18 (1) 184-198; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0012
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  Aberrantly expressed GFRα-1/RET in patients with lacrimal adenoid cystic carcinoma is associated with high recurrence risk: a retrospective study of 51 LACC cases

  Lin Liu, Liqiong Zhao, Jie Zhang, Guoxiang Song, Carol L. Shields and Ruihua Wei

  Cancer Biology & Medicine February 2021, 18 (1) 199-205; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0271
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  Inhibition of focal adhesion kinase enhances antitumor response of radiation therapy in pancreatic cancer through CD8+ T cells

  Arsen Osipov, Alex B. Blair, Juliane Liberto, Jianxin Wang, Keyu Li, Brian Herbst, Yao Xu, Shiqi Li, Nan Niu, Rufiaat Rashid, Ding Ding, Yanan Liu, Zaiqi Wang, Christopher L. Wolfgang, Richard A. Burkhart, Daniel Laheru and Lei Zheng

  Cancer Biology & Medicine February 2021, 18 (1) 206-214; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0273
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  A truncated protein product of the germline variant of the DUOX2 gene leads to adenomatous polyposis

  Mengyuan Yang, Yingxin Zhao, Yuwei Ding, Juan Wang, Yinuo Tan, Dong Xu and Ying Yuan

  Cancer Biology & Medicine February 2021, 18 (1) 215-226; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0305
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  Nobiletin downregulates the SKP2-p21/p27-CDK2 axis to inhibit tumor progression and shows synergistic effects with palbociclib on renal cell carcinoma

  Tingting Chen, Liu Liu, Yonghong Zou, Xiaoyan Hu, Wenfeng Zhang, Tao Zhou, Xi Luo, Weihua Fu and Jie Xu

  Cancer Biology & Medicine February 2021, 18 (1) 227-244; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0186
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  Reduced anoctamin 7 (ANO7) expression is a strong and independent predictor of poor prognosis in prostate cancer

  Andreas Marx, Lena Koopmann, Doris Höflmayer, Franziska Büscheck, Claudia Hube-Magg, Stefan Steurer, Till Eichenauer, Till S. Clauditz, Waldemar Wilczak, Ronald Simon, Guido Sauter, Jakob R. Izbicki, Hartwig Huland, Hans Heinzer, Markus Graefen, Alexander Haese, Thorsten Schlomm, Christian Bernreuther, Patrick Lebok and Sarah Bonk

  Cancer Biology & Medicine February 2021, 18 (1) 245-255; DOI: https://doi.org/10.20892/j.issn.2095-3941.2019.0324
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  Diagnostic value of 5 serum biomarkers for hepatocellular carcinoma with different epidemiological backgrounds: A large-scale, retrospective study

  Dongming Liu, Yi Luo, Lu Chen, Liwei Chen, Duo Zuo, Yueguo Li, Xiaofang Zhang, Jing Wu, Qing Xi, Guangtao Li, Lisha Qi, Xiaofen Yue, Xiehua Zhang, Zhuoyu Sun, Ning Zhang, Tianqiang Song, Wei Lu and Hua Guo

  Cancer Biology & Medicine February 2021, 18 (1) 256-270; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0207
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  Predictive value of MGMT promoter methylation on the survival of TMZ treated IDH-mutant glioblastoma

  Ruichao Chai, Guanzhang Li, Yuqing Liu, Kenan Zhang, Zheng Zhao, Fan Wu, Yuzhou Chang, Bo Pang, Jingjun Li, Yangfang Li, Tao Jiang and Yongzhi Wang

  Cancer Biology & Medicine February 2021, 18 (1) 271-282; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0179
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  Association of systemic inflammation and body mass index with survival in patients with resectable gastric or gastroesophageal junction adenocarcinomas

  Xianchun Gao, Yanan Pan, Weili Han, Caie Hu, Chenchen Wang, Ling Chen, Yong Guo, Yupeng Shi, Yan Pan, Huahong Xie, Liping Yao, Jianjun Yang, Jianyong Zheng, Xiaohua Li, Xiaonan Liu, Liu Hong, Jipeng Li, Mengbin Li, Gang Ji, Zengshan Li, Jielai Xia, Qingchuan Zhao, Daiming Fan, Kaichun Wu and Yongzhan Nie

  Cancer Biology & Medicine February 2021, 18 (1) 283-297; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0246
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  Effects of cancer on patients with COVID-19: a systematic review and meta-analysis of 63,019 participants

  Ludi Yang, Peiwei Chai, Jie Yu and Xianqun Fan

  Cancer Biology & Medicine February 2021, 18 (1) 298-307; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0559
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  A multi-institutional retrospective study of hyperthermic plus intravesical chemotherapy versus intravesical chemotherapy treatment alone in intermediate and high risk nonmuscle-invasive bladder cancer

  Qiang Ruan, Degang Ding, Bin Wang, Chaohong He, Xuequn Ren, Zhenhua Feng, Zhigang Pang, Jin Wang, Xiangliang Zhang, Hongsheng Tang, Jiahong Wang, Qingjun He, Ziying Lei, Quanxing Liao, Jiali Luo and Shuzhong Cui

  Cancer Biology & Medicine February 2021, 18 (1) 308-317; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0125