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Research ArticleOriginal Article

The mutational pattern of homologous recombination (HR)-associated genes and its relevance to the immunotherapeutic response in gastric cancer

Yue Fan, Haifeng Ying, Xueying Wu, Huan Chen, Ying Hu, Henghui Zhang, Lijia Wu, Ying Yang, Beibei Mao and Lan Zheng
Cancer Biology & Medicine November 2020, 17 (4) 1002-1013; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0089
Yue Fan
1Department of integrated Traditional Chinese Medicine and Western Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China
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Haifeng Ying
2Department of Traditional Chinese Medicine, Ruijin Hospital, Shanghai Jiaotong University, Shanghai 200025, China
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Xueying Wu
3Genecast Precision Medicine Technology Institute, Beijing 100191, China
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Huan Chen
3Genecast Precision Medicine Technology Institute, Beijing 100191, China
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Ying Hu
4Center of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China
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Henghui Zhang
3Genecast Precision Medicine Technology Institute, Beijing 100191, China
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Lijia Wu
3Genecast Precision Medicine Technology Institute, Beijing 100191, China
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Ying Yang
3Genecast Precision Medicine Technology Institute, Beijing 100191, China
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Beibei Mao
3Genecast Precision Medicine Technology Institute, Beijing 100191, China
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  • ORCID record for Beibei Mao
  • For correspondence: zl10558{at}rjh.com.cn mao.beibei{at}genecast.com.cn
Lan Zheng
2Department of Traditional Chinese Medicine, Ruijin Hospital, Shanghai Jiaotong University, Shanghai 200025, China
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  • ORCID record for Lan Zheng
  • For correspondence: zl10558{at}rjh.com.cn mao.beibei{at}genecast.com.cn
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The mutational pattern of homologous recombination (HR)-associated genes and its relevance to the immunotherapeutic response in gastric cancer
Yue Fan, Haifeng Ying, Xueying Wu, Huan Chen, Ying Hu, Henghui Zhang, Lijia Wu, Ying Yang, Beibei Mao, Lan Zheng
Cancer Biology & Medicine Nov 2020, 17 (4) 1002-1013; DOI: 10.20892/j.issn.2095-3941.2020.0089

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The mutational pattern of homologous recombination (HR)-associated genes and its relevance to the immunotherapeutic response in gastric cancer
Yue Fan, Haifeng Ying, Xueying Wu, Huan Chen, Ying Hu, Henghui Zhang, Lijia Wu, Ying Yang, Beibei Mao, Lan Zheng
Cancer Biology & Medicine Nov 2020, 17 (4) 1002-1013; DOI: 10.20892/j.issn.2095-3941.2020.0089
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Keywords

  • Gastric cancer
  • homologous recombination deficiency
  • immunotherapy
  • biomarker

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