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Review ArticleReview

Comprehensive insights into the effects and regulatory mechanisms of immune cells expressing programmed death-1/programmed death ligand 1 in solid tumors

Min Liu, Qian Sun, Feng Wei and Xiubao Ren
Cancer Biology & Medicine August 2020, 17 (3) 626-639; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0112
Min Liu
1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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Qian Sun
1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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Feng Wei
1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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Xiubao Ren
1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
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  • For correspondence: renxiubao{at}tjmuch.com
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Article Information

vol. 17 no. 3 626-639
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2020.0112

Published By 
Cancer Biology & Medicine
History 
  • Received March 14, 2020
  • Accepted June 8, 2020
  • Published online August 15, 2020.

Copyright & Usage 
Copyright: © 2020, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Author Information

  1. Min Liu1,
  2. Qian Sun1,
  3. Feng Wei1 and
  4. Xiubao Ren1⇑
  1. 1Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
  1. Correspondence to: Xiubao Ren, E-mail: renxiubao{at}tjmuch.com
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Cancer Biology and Medicine: 17 (3)
Cancer Biology & Medicine
Vol. 17, Issue 3
15 Aug 2020
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Comprehensive insights into the effects and regulatory mechanisms of immune cells expressing programmed death-1/programmed death ligand 1 in solid tumors
Min Liu, Qian Sun, Feng Wei, Xiubao Ren
Cancer Biology & Medicine Aug 2020, 17 (3) 626-639; DOI: 10.20892/j.issn.2095-3941.2020.0112

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Comprehensive insights into the effects and regulatory mechanisms of immune cells expressing programmed death-1/programmed death ligand 1 in solid tumors
Min Liu, Qian Sun, Feng Wei, Xiubao Ren
Cancer Biology & Medicine Aug 2020, 17 (3) 626-639; DOI: 10.20892/j.issn.2095-3941.2020.0112
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  • Article
    • Abstract
    • Introduction
    • Immune cells with high expression of PD-1 or PD-L1 help predict tumor progression and prognosis
    • Effects of immune cells with high expression of PD-1 or PD-L1 in tumor immunity
    • Regulation of PD-1 or PD-L1 expression on immune cells in tumor immunity
    • Potential therapeutic strategies of anti-PD-L1/PD-1 therapy
    • Conclusions
    • Acknowledgments
    • Footnotes
    • References
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Keywords

  • Immune cell
  • immunotherapy
  • programmed cell death ligand 1
  • programmed cell death-1
  • solid tumor

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