Research ArticleOriginal Article

Heat shock protein 47 promotes tumor survival and therapy resistance by modulating AKT signaling via PHLPP1 in colorectal cancer

Yijye Chern, Peter Zhang, Hyelim Ju and Isabella T. Tai
Cancer Biology & Medicine May 2020, 17 (2) 343-356; DOI: https://doi.org/10.20892/j.issn.2095-3941.2019.0261

Article Information

vol. 17 no. 2 343-356
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2019.0261
Published By 
Cancer Biology & Medicine
History 
  • Received July 25, 2019
  • Accepted December 3, 2019
  • Published online May 15, 2020.
Copyright & Usage 
Copyright: © 2020, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Author Information

  1. Yijye Chern1,2,
  2. Peter Zhang1,2,
  3. Hyelim Ju1,2 and
  4. Isabella T. Tai1,2⇑
  1. 1Division of Gastroenterology, Department of Medicine, University of British Columbia, Vancouver V6T 1Z4, Canada
  2. 2Michael Smith Genome Sciences Center, British Columbia Cancer Agency, Vancouver V5Z 4S6, Canada
  1. Correspondence to: Isabella T. Tai. E-mail: itai{at}bcgsc.ca
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