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Review ArticleReview

Epigenetic N6-methyladenosine modification of RNA and DNA regulates cancer

Zhixian Liang, Reilly L. Kidwell, Haijing Deng and Qi Xie
Cancer Biology & Medicine February 2020, 17 (1) 9-19; DOI: https://doi.org/10.20892/j.issn.2095-3941.2019.0347
Zhixian Liang
1School of Life Sciences, Westlake University, Hangzhou 310024, China
2Institute of Biology, Westlake Institute for Advanced Study, Hangzhou 310024, China
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Reilly L. Kidwell
3Division of Regenerative Medicine, Department of Medicine, University of California San Diego, San Diego, CA 92037, USA
4University of California San Diego, School of Medicine, La Jolla, CA 92037, USA
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Haijing Deng
1School of Life Sciences, Westlake University, Hangzhou 310024, China
2Institute of Biology, Westlake Institute for Advanced Study, Hangzhou 310024, China
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Qi Xie
1School of Life Sciences, Westlake University, Hangzhou 310024, China
2Institute of Biology, Westlake Institute for Advanced Study, Hangzhou 310024, China
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  • ORCID record for Qi Xie
  • For correspondence: xieqi{at}westlake.edu.cn
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Article Information

vol. 17 no. 1 9-19
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2019.0347

Published By 
Cancer Biology & Medicine
History 
  • Received December 14, 2019
  • Accepted January 2, 2020
  • Published online February 15, 2020.

Copyright & Usage 
Copyright: © 2020, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Author Information

  1. Zhixian Liang1,2,*,
  2. Reilly L. Kidwell3,4,*,
  3. Haijing Deng1,2 and
  4. Qi Xie1,2⇑
  1. 1School of Life Sciences, Westlake University, Hangzhou 310024, China
  2. 2Institute of Biology, Westlake Institute for Advanced Study, Hangzhou 310024, China
  3. 3Division of Regenerative Medicine, Department of Medicine, University of California San Diego, San Diego, CA 92037, USA
  4. 4University of California San Diego, School of Medicine, La Jolla, CA 92037, USA
  1. Correspondence to: Qi Xie, E-mail: xieqi{at}westlake.edu.cn
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Cancer Biology and Medicine: 17 (1)
Cancer Biology & Medicine
Vol. 17, Issue 1
15 Feb 2020
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Epigenetic N6-methyladenosine modification of RNA and DNA regulates cancer
Zhixian Liang, Reilly L. Kidwell, Haijing Deng, Qi Xie
Cancer Biology & Medicine Feb 2020, 17 (1) 9-19; DOI: 10.20892/j.issn.2095-3941.2019.0347

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Epigenetic N6-methyladenosine modification of RNA and DNA regulates cancer
Zhixian Liang, Reilly L. Kidwell, Haijing Deng, Qi Xie
Cancer Biology & Medicine Feb 2020, 17 (1) 9-19; DOI: 10.20892/j.issn.2095-3941.2019.0347
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  • Article
    • Abstract
    • Introduction
    • The roles of RNA m6A in human cancer
    • The roles of DNA 6mA in human cancer
    • Clinical applications of N6-methyladenosine
    • Conclusions and perspectives
    • Acknowledgements
    • Footnotes
    • References
  • Figures & Data
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  • References
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Keywords

  • N6-methyladenosine
  • RNA methylation
  • DNA methylation
  • cancer
  • therapeutic targets

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