Research ArticleOriginal Article

Clinical characteristics and work-up of small to intermediate-sized pulmonary nodules in a Chinese dedicated cancer hospital

Xiaonan Cui, Daiwei Han, Marjolein A. Heuvelmans, Yihui Du, Yingru Zhao, Lei Zhang, Harry J.M. Groen, Geertruida H. de Bock, Monique D. Dorrius, Matthijs Oudkerk, Rozemarijn Vliegenthart and Zhaoxiang Ye
Cancer Biology & Medicine February 2020, 17 (1) 199-207; DOI: https://doi.org/10.20892/j.issn.2095-3941.2019.0028

References

  1. 1.↵
    2. Chen WQ,
    3. Zheng RS,
    4. Baade PD,
    5. Zhang SW,
    6. Zeng HM,
    7. Bray F, et al.
    Cancer statistics in China, 2015. CA J Clin. 2016; 66: 115–32.
    OpenUrlCrossRefPubMed
  2. 2.↵
    2. Oudkerk M,
    3. Devaraj A,
    4. Vliegenthart R,
    5. Henzler T,
    6. Prosch H,
    7. Heussel CP, et al.
    European position statement on lung cancer screening. Lancet Oncol. 2017; 18: e754–66.
    OpenUrlCrossRefPubMed
  3. 3.↵
    2. Liang WH,
    3. Shao WL,
    4. Jiang GN,
    5. Wang Q,
    6. Liu LX,
    7. Liu DR, et al.
    Chinese multi-institutional registry (CMIR) for resected non-small cell lung cancer: survival analysis of 5,853 cases. J Thorac Dis. 2013; 5: 726–9.
    OpenUrl
  4. 4.↵
    2. Yang WJ,
    3. Qian FF,
    4. Teng JJ,
    5. Wang HM,
    6. Manegold C,
    7. Pilz LR, et al.
    Community-based lung cancer screening with low-dose CT in China: results of the baseline screening. Lung Cancer. 2018; 117: 20–6.
    OpenUrl
  5. 5.↵
    2. Aberle DR,
    3. Adams AM,
    4. Berg CD,
    5. Black WC,
    6. Clapp JD,
    7. Fagerstrom RM, et al.
    Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011; 365: 395–409.
    OpenUrlCrossRefPubMedWeb of Science
  6. 6.↵
    2. Swensen SJ,
    3. Silverstein MD,
    4. Ilstrup DM,
    5. Schleck CD,
    6. Edell ES.
    The probability of malignancy in solitary pulmonary nodules. Application to small radiologically indeterminate nodules. Arch Intern Med. 1997; 157: 849–55.
    OpenUrlCrossRefPubMedWeb of Science
  7. 7.
    2. Gould MK,
    3. Ananth L,
    4. Barnett PG.
    A clinical model to estimate the pretest probability of lung cancer in patients with solitary pulmonary nodules. Chest. 2007; 131: 383–8.
    OpenUrlCrossRefPubMedWeb of Science
  8. 8.↵
    2. Chung K,
    3. Mets OM,
    4. Gerke PK,
    5. Jacobs C,
    6. den Harder AM,
    7. Scholten ET, et al.
    Brock malignancy risk calculator for pulmonary nodules: validation outside a lung cancer screening population. Thorax. 2018; 73: 857–63.
    OpenUrlAbstract/FREE Full Text
  9. 9.↵
    2. Tanner NT,
    3. Porter A,
    4. Gould MK,
    5. Li XJ,
    6. Vachani A,
    7. Silvestri GA.
    Physician assessment of pretest probability of malignancy and adherence with guidelines for pulmonary nodule evaluation. Chest. 2017; 152: 263–70.
    OpenUrl
  10. 10.↵
    2. Zhou W,
    3. Christiani DC.
    East meets West: ethnic differences in epidemiology and clinical behaviors of lung cancer between East Asians and Caucasians. Chin J Cancer. 2011; 30: 287–92.
    OpenUrlCrossRefPubMed
  11. 11.↵
    2. Hu J,
    3. Qian G-S,
    4. Bai C-X.
    Society LCSGotCT, Group tCAALCE. Chinese consensus on early diagnosis of primary lung cancer (2014 version). Cancer. 2015; 121: 3157–64.
    OpenUrlCrossRef
  12. 12.↵
    2. Tang W,
    3. Wu N,
    4. Huang Y,
    5. Wang JW,
    6. Zhao SJ,
    7. Xu ZJ, et al.
    Results of low-dose computed tomography (LDCT) screening for early lung cancer: prevalence in 4 690 asymptomatic participants. Chin J Oncol. 2014; 36: 549–54.
    OpenUrl
  13. 13.↵
    2. Gao ZS,
    3. Ye ZX,
    4. Zhang P,
    5. Cui XN,
    6. Xie YS,
    7. Han LZ.
    Low-dose computed tomography screening for lung cancer in Tianjin: a preliminary clinical analysis of baseline screening and follow-up results. Chin J Clin Oncol. 2017; 44: 1034–9.
    OpenUrl
  14. 14.↵
    2. Jemal A,
    3. Bray F,
    4. Center MM,
    5. Ferlay J,
    6. Ward E,
    7. Forman D.
    Global cancer statistics. CA: A Cancer J Clin. 2011; 61: 69–90.
    OpenUrlCrossRef
  15. 15.↵
    2. Kawaguchi T,
    3. Matsumura A,
    4. Fukai S,
    5. Tamura A,
    6. Saito R,
    7. Zell JA, et al.
    Japanese ethnicity compared with Caucasian ethnicity and never-smoking status are independent favorable prognostic factors for overall survival in non-small cell lung cancer: a collaborative epidemiologic study of the National Hospital Organization Study Group for Lung Cancer (NHSGLC) in Japan and a southern California Regional cancer registry databases. J Thorac Oncol. 2010; 5: 1001–10.
    OpenUrlCrossRefPubMedWeb of Science
  16. 16.
    2. Zhang H,
    3. Cai BQ.
    The impact of tobacco on lung health in China. Respirology. 2003; 8: 17–21.
    OpenUrlCrossRefPubMedWeb of Science
  17. 17.↵
    2. She J,
    3. Yang P,
    4. Hong QY,
    5. Bai CX.
    Lung cancer in China: challenges and interventions. Chest. 2013; 143: 1117–26.
    OpenUrlCrossRefPubMed
  18. 18.↵
    2. Ren SX,
    3. Kuang P,
    4. Zheng LM,
    5. Su CX,
    6. Li JY,
    7. Li B, et al.
    Analysis of driver mutations in female non-smoker Asian patients with pulmonary adenocarcinoma. Cell Biochem Biophys. 2012; 64: 155–60.
    OpenUrlPubMed
  19. 19.
    2. Ni X,
    3. Xu N,
    4. Wang Q.
    Meta-analysis and systematic review in environmental tobacco smoke risk of female lung cancer by research type. Int J Environ Res Public Health. 2018; 15: 1348.
    OpenUrl
  20. 20.↵
    2. Donner I,
    3. Katainen R,
    4. Sipila LJ,
    5. Aavikko M,
    6. Pukkala E,
    7. Aaltonen LA.
    Germline mutations in young non-smoking women with lung adenocarcinoma. Lung Cancer. 2018; 122: 76–82.
    OpenUrl
  21. 21.↵
    2. Zhou QH,
    3. Fan YG,
    4. Wang Y,
    5. Qiao YL,
    6. Wang GQ,
    7. Huang YC, et al.
    China national guideline of classification, diagnosis and treatment for lung nodules (2016 Version). Chin J Lung Cancer. 2016; 19: 793–8.
    OpenUrl
  22. 22.
    2. MacMahon H,
    3. Naidich DP,
    4. Goo JM,
    5. Lee KS,
    6. Leung ANC,
    7. Mayo JR, et al.
    Guidelines for management of incidental pulmonary nodules detected on CT images: from the Fleischner Society 2017. Radiology. 2017; 284: 228–43.
    OpenUrlCrossRefPubMed
  23. 23.↵
    2. Walter JE,
    3. Heuvelmans MA,
    4. Yousaf-Khan U,
    5. Dorrius MD,
    6. Thunnissen E,
    7. Schermann A, et al.
    New subsolid pulmonary nodules in lung cancer screening: the NELSON trial. J Thorac Oncol. 2018; 13: 1410–4.
    OpenUrlPubMed
  24. 24.↵
    2. Xu DM,
    3. van der Zaag-Loonen HJ,
    4. Oudkerk M,
    5. Wang Y,
    6. Vliegenthart R,
    7. Scholten ET, et al.
    Smooth or attached solid indeterminate nodules detected at baseline CT screening in the NELSON study: cancer risk during 1 year of follow-up. Radiology. 2009; 250: 264–72.
    OpenUrlCrossRefPubMedWeb of Science
  25. 25.
    2. van’t Westeinde SC,
    3. de Koning HJ,
    4. Xu DM,
    5. Hoogsteden HC,
    6. van Klaveren RJ.
    How to deal with incidentally detected pulmonary nodules less than 10 mm in size on CT in a healthy person. Lung Cancer. 2008; 60: 151–9.
    OpenUrlCrossRefPubMedWeb of Science
  26. 26.
    2. Zhao YR,
    3. Heuvelmans MA,
    4. Dorrius MD,
    5. van Ooijen PMA,
    6. Wang Y,
    7. de Bock GH, et al.
    Features of resolving and nonresolving indeterminate pulmonary nodules at follow-up CT: the NELSON study. Radiology. 2014; 270: 872–9.
    OpenUrlCrossRefPubMed
  27. 27.↵
    2. Lindell RM,
    3. Hartman TE,
    4. Swensen SJ,
    5. Jett JR,
    6. Midthun DE,
    7. Tazelaar HD, et al.
    Five-year lung cancer screening experience: CT appearance, growth rate, location, and histologic features of 61 lung cancers. Radiology. 2007; 242: 555–62.
    OpenUrlCrossRefPubMedWeb of Science
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