Research ArticleOriginal Article

Coagulation factor VII gene polymorphisms are not associated with the occurrence or the survival of hepatocellular carcinoma: a report of 37 cases

Chih-Che Lin, Chun-Hsien Wu, Li-Yu Chen, Ming-Chao Tsai, Ahmed M. Elsarawy and Kuang-Tzu Huang
Cancer Biology & Medicine August 2018, 15 (3) 275-281; DOI: https://doi.org/10.20892/j.issn.2095-3941.2017.0144

References

  1. 1.↵
    2. Blom JW,
    3. Doggen CJM,
    4. Osanto S,
    5. Rosendaal FR.
    Malignancies, prothrombotic mutations, and the risk of venous thrombosis. JAMA. 2005; 293: 715–22.
    OpenUrlCrossRefPubMedWeb of Science
  2. 2.↵
    2. Horowitz N,
    3. Brenner B.
    Thrombophilia and cancer. Pathophysiol Haemos Thromb. 2008; 36: 131–6.
    OpenUrl
  3. 3.↵
    2. Furie B,
    3. Furie BC.
    The molecular basis of blood coagulation. Cell. 1988; 53: 505–18.
    OpenUrlCrossRefPubMedWeb of Science
  4. 4.↵
    2. Versteeg HH,
    3. Peppelenbosch MP,
    4. Spek CA.
    The pleiotropic effects of tissue factor: a possible role for factor VIIa-induced intracellular signalling?. Thromb Haemost. 2001; 86: 1353–9.
    OpenUrlPubMedWeb of Science
  5. 5.↵
    2. Versteeg HH,
    3. Ruf W.
    Emerging insights in tissue factor-dependent signaling events. Semin Thromb Hemost. 2006; 32: 24–32.
    OpenUrlCrossRefPubMedWeb of Science
  6. 6.↵
    2. Rak J.
    Microparticles in cancer. Semin Thromb Hemost. 2010; 36: 888–906.
    OpenUrlCrossRefPubMed
  7. 7.↵
    2. Waly Raphael S,
    3. Zhang YD,
    4. Chen YX.
    Hepatocellular carcinoma: focus on different aspects of management. ISRN Oncol. 2012; 2012: 421673.
    OpenUrlPubMed
  8. 8.↵
    2. Best J,
    3. Schotten C,
    4. Theysohn JM,
    5. Wetter A,
    6. Muller S,
    7. Radunz S, et al.
    Novel implications in the treatment of hepatocellular carcinoma. Ann Gastroenterol. 2017; 30: 23–32.
    OpenUrl
  9. 9.↵
    2. Omata M,
    3. Lesmana LA,
    4. Tateishi R,
    5. Chen PJ,
    6. Lin SM,
    7. Yoshida H, et al.
    Asian Pacific Association for the Study of the Liver consensus recommendations on hepatocellular carcinoma. Hepatol Int. 2010; 4: 439–74.
    OpenUrlCrossRefPubMed
  10. 10.↵
    2. Chen KD,
    3. Huang KT,
    4. Tsai MC,
    5. Wu CH,
    6. Kuo IY,
    7. Chen LY, et al.
    Coagulation factor VII and malignant progression of hepatocellular carcinoma. Cell Death Dis. 2016; 7: e2110.
    OpenUrl
  11. 11.
    2. Chen KD,
    3. Wang CC,
    4. Tsai MC,
    5. Wu CH,
    6. Yang HJ,
    7. Chen LY, et al.
    Interconnections between autophagy and the coagulation cascade in hepatocellular carcinoma. Cell Death Dis. 2014; 5: e1244.
  12. 12.↵
    2. Tsai MC,
    3. Chen KD,
    4. Wang CC,
    5. Huang KT,
    6. Wu CH,
    7. Kuo IY, et al.
    Factor VII promotes hepatocellular carcinoma progression through ERK-TSC signaling. Cell Death Discov. 2015; 1: 15051.
    OpenUrl
  13. 13.↵
    2. Pollak ES,
    3. Hung HL,
    4. Godin W,
    5. Overton GC,
    6. High KA.
    Functional characterization of the human factor VII 5'-flanking region. J Biol Chem. 1996; 271: 1738–47.
    OpenUrlAbstract/FREE Full Text
  14. 14.↵
    2. van't Hooft FM,
    3. Silveira A,
    4. Tornvall P,
    5. Iliadou A,
    6. Ehrenborg E,
    7. Eriksson P, et al.
    Two common functional polymorphisms in the promoter region of the coagulation factor VII gene determining plasma factor VII activity and mass concentration. Blood. 1999; 93: 3432–41.
    OpenUrlAbstract/FREE Full Text
  15. 15.↵
    2. Sabater-Lleal M,
    3. Chillón M,
    4. Howard TE,
    5. Gil E,
    6. Almasy L,
    7. Blangero J, et al.
    Functional analysis of the genetic variability in the F7 gene promoter. Atherosclerosis. 2007; 195: 262–8.
    OpenUrlPubMed
  16. 16.↵
    2. Eroğlu A,
    3. Öztürk A,
    4. Akar N.
    Association between the -402GA, -401GT, and -323ins10-bp polymorphisms of factor VII gene and breast cancer. Breast Cancer. 2011; 18: 282–5.
    OpenUrlPubMed
  17. 17.↵
    2. Buxhofer-Ausch V,
    3. Olcaydu D,
    4. Gisslinger B,
    5. Schalling M,
    6. Frantal S,
    7. Thiele J, et al.
    Decanucleotide insertion polymorphism of F7 significantly influences the risk of thrombosis in patients with essential thrombocythemia. Eur J Haematol. 2014; 93: 103–11.
    OpenUrlCrossRefPubMed
  18. 18.
    2. de Maat MP,
    3. Green F,
    4. de Knijff P,
    5. Jespersen J,
    6. Kluft C.
    Factor VII polymorphisms in populations with different risks of cardiovascular disease. Arterioscler, Thromb, Vasc Biol. 1997; 17: 1918–23.
    OpenUrlAbstract/FREE Full Text
  19. 19.↵
    2. Meade TW,
    3. Brozovic M,
    4. Chakrabarti RR,
    5. Haines AP,
    6. Imeson JD,
    7. Mellows S, et al.
    Haemostatic function and ischaemic heart disease: principal results of the Northwick Park Heart Study. Lancet. 1986; 328: 533–7.
    OpenUrlCrossRef
  20. 20.↵
    2. Bernardi F,
    3. Marchetti G,
    4. Pinotti M,
    5. Arcieri P,
    6. Baroncini C,
    7. Papacchini M, et al.
    Factor VII gene polymorphisms contribute about one third of the factor VII level variation in plasma. Arterioscler, Thromb, Vasc Biol. 1996; 16: 72–6.
    OpenUrlPubMedWeb of Science
  21. 21.↵
    2. Iacoviello L,
    3. di Castelnuovo A,
    4. de Knijff P,
    5. D'Orazio A,
    6. Amore C,
    7. Arboretti R, et al.
    Polymorphisms in the coagulation factor VII gene and the risk of myocardial infarction. N Engl J Med. 1998; 338: 79–85.
    OpenUrlCrossRefPubMedWeb of Science
  22. 22.↵
    2. Lopaciuk S,
    3. Windyga J,
    4. Watala CW,
    5. Bykowska K,
    6. Pietrucha T,
    7. Kwiecinski H, et al.
    Polymorphisms in the factor VII gene and ischemic stroke in young adults. Blood Coagul Fibrinolysis. 2010; 21: 442–7.
    OpenUrlCrossRefPubMed
  23. 23.↵
    2. Doggen CJM,
    3. Cats MV,
    4. Bertina RM,
    5. Reitsma PH,
    6. Vandenbroucke JP,
    7. Rosendaal FR.
    A genetic propensity to high factor VII is not associated with the risk of myocardial infarction in men. Thromb Haemost. 1998; 80: 281–5.
    OpenUrlPubMedWeb of Science
  24. 24.↵
    2. Ken-Dror G,
    3. Drenos F,
    4. Humphries SE,
    5. Talmud PJ,
    6. Hingorani AD,
    7. Kivimäki M,
    8. Kumari M, et al.
    Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men. J Thromb Haemost. 2010; 8: 2394–403.
    OpenUrlCrossRefPubMedWeb of Science
  25. 25.↵
    2. Li C,
    3. Li R,
    4. Zhang W.
    Progress in non-invasive detection of liver fibrosis. Cancer Biol Med. 2018; 15: 124–36.
    OpenUrlAbstract/FREE Full Text
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