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Review ArticleReview

Key questions about the checkpoint blockade-are microRNAs an answer?

Mihnea Dragomir, Baoqing Chen, Xiao Fu and George A. Calin
Cancer Biology & Medicine May 2018, 15 (2) 103-115; DOI: https://doi.org/10.20892/j.issn.2095-3941.2018.0006
Mihnea Dragomir
1Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA
2Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca 400012, Romania
3Department of Surgery, Fundeni Clinical Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest 4192910, Romania
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Baoqing Chen
1Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA
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Xiao Fu
1Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA
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George A. Calin
1Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA
4Center for RNA Interference and Non-coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA
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  • For correspondence: gcalin{at}mdanderson.org
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Cancer Biology and Medicine: 15 (2)
Cancer Biology & Medicine
Vol. 15, Issue 2
1 May 2018
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Key questions about the checkpoint blockade-are microRNAs an answer?
Mihnea Dragomir, Baoqing Chen, Xiao Fu, George A. Calin
Cancer Biology & Medicine May 2018, 15 (2) 103-115; DOI: 10.20892/j.issn.2095-3941.2018.0006

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Key questions about the checkpoint blockade-are microRNAs an answer?
Mihnea Dragomir, Baoqing Chen, Xiao Fu, George A. Calin
Cancer Biology & Medicine May 2018, 15 (2) 103-115; DOI: 10.20892/j.issn.2095-3941.2018.0006
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    • Introduction
    • MiRNAs control immune checkpoints expression
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Keywords

  • microRNA
  • PD-1
  • PD-L1
  • CTLA-4
  • checkpoint inhibitors

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