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Research ArticleOriginal Article

Modulation of B-cell receptor and microenvironment signaling by a guanine exchange factor in B-cell malignancies

Wei Liao and Sanjai Sharma
Cancer Biology & Medicine June 2016, 13 (2) 277-285; DOI: https://doi.org/10.20892/j.issn.2095-3941.2016.0026
Wei Liao
1Division of Hematology-Oncology, Greater Los Angeles VA Healthcare Center, UCLA School of Medicine, Los Angeles, CA 90073, USA
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Sanjai Sharma
1Division of Hematology-Oncology, Greater Los Angeles VA Healthcare Center, UCLA School of Medicine, Los Angeles, CA 90073, USA
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  • For correspondence: sasharma{at}mednet.ucla.edu
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Article Information

vol. 13 no. 2 277-285
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2016.0026

Published By 
Cancer Biology & Medicine
History 
  • Received January 5, 2016
  • Accepted January 4, 2016
  • Published online June 1, 2016.

Copyright & Usage 
Copyright: © 2016, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Author Information

  1. Wei Liao1 and
  2. Sanjai Sharma1⇑
  1. 1Division of Hematology-Oncology, Greater Los Angeles VA Healthcare Center, UCLA School of Medicine, Los Angeles, CA 90073, USA
  1. Correspondence to: Sanjai Sharma, E-mail: sasharma{at}mednet.ucla.edu
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Cancer Biology and Medicine: 13 (2)
Cancer Biology & Medicine
Vol. 13, Issue 2
1 Jun 2016
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Modulation of B-cell receptor and microenvironment signaling by a guanine exchange factor in B-cell malignancies
Wei Liao, Sanjai Sharma
Cancer Biology & Medicine Jun 2016, 13 (2) 277-285; DOI: 10.20892/j.issn.2095-3941.2016.0026

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Modulation of B-cell receptor and microenvironment signaling by a guanine exchange factor in B-cell malignancies
Wei Liao, Sanjai Sharma
Cancer Biology & Medicine Jun 2016, 13 (2) 277-285; DOI: 10.20892/j.issn.2095-3941.2016.0026
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Keywords

  • B-cell malignancies
  • Mantle cell lymphoma
  • chronic lymphocytic leukemia (CLL)
  • B-cell receptor
  • guanine exchange factor
  • Rasgrf-1
  • ERK pathway

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