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Review ArticleReview

Relationship of VEGF/VEGFR with immune and cancer cells: staggering or forward?

Yu-Ling Li, Hua Zhao and Xiu-Bao Ren
Cancer Biology & Medicine June 2016, 13 (2) 206-214; DOI: https://doi.org/10.20892/j.issn.2095-3941.2015.0070
Yu-Ling Li
1Department of Biotherapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China
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Hua Zhao
1Department of Biotherapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China
2Key Laboratory of Cancer Immunology and Biotherapy, Research Center of Lung Cancer, Tianjin 300060, China
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Xiu-Bao Ren
1Department of Biotherapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China
2Key Laboratory of Cancer Immunology and Biotherapy, Research Center of Lung Cancer, Tianjin 300060, China
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Article Information

vol. 13 no. 2 206-214
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2015.0070

Published By 
Cancer Biology & Medicine
History 
  • Received September 7, 2015
  • Accepted November 19, 2015
  • Published online June 1, 2016.

Copyright & Usage 
Copyright: © 2016, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Author Information

  1. Yu-Ling Li1,
  2. Hua Zhao1,2 and
  3. Xiu-Bao Ren1,2⇑
  1. 1Department of Biotherapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China
  2. 2Key Laboratory of Cancer Immunology and Biotherapy, Research Center of Lung Cancer, Tianjin 300060, China
  1. Correspondence to: Xiu-Bao Ren, E-mail: renxiubao{at}tjmuch.com
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Cancer Biology and Medicine: 13 (2)
Cancer Biology & Medicine
Vol. 13, Issue 2
1 Jun 2016
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Relationship of VEGF/VEGFR with immune and cancer cells: staggering or forward?
Yu-Ling Li, Hua Zhao, Xiu-Bao Ren
Cancer Biology & Medicine Jun 2016, 13 (2) 206-214; DOI: 10.20892/j.issn.2095-3941.2015.0070

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Relationship of VEGF/VEGFR with immune and cancer cells: staggering or forward?
Yu-Ling Li, Hua Zhao, Xiu-Bao Ren
Cancer Biology & Medicine Jun 2016, 13 (2) 206-214; DOI: 10.20892/j.issn.2095-3941.2015.0070
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  • Article
    • Abstract
    • Introduction
    • Biology of VEGF
    • Biology of VEGFRs
    • Relationship between VEGF/VEGFR and DCs
    • Relationship between VEGF/VEGFR and macrophages
    • Relationship between VEGF/VEGFR and T cells
    • VEGF can be secreted by tumor cells and further stimulate cancer stemness
    • Conclusions
    • Acknowledgements
    • Footnotes
    • References
  • Figures & Data
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  • References
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Keywords

  • Vascular endothelial growth factor (VEGF)
  • VEGF receptors (VEGFRs)
  • dendritic cell (DC)
  • macrophage
  • T lymphocyte
  • tumor

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