Analysis of 30 patients with persistent or recurrent squamous cell carcinoma of the cervix within one year after concurrent chemoradiotherapy

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Figure 1
Overall survival of patients with persistent or recurrent disease.

Table 1

Sites of recurrence, n (%)

Recurrence pattern	n (%)
Local failure or recurrence	5 (16.7)
Limited to cervix	2 (6.7)
Beyond cervix but inside pelvis	3 (10.0)
Distant metastasis	21 (70.0)
Limited to PALN	1 (3.3)
Limited to SCLN (with or without SCLN metastasis)	3 (10.0)
Beyond SCLN and PALN (lung, bone, liver, ect.)	17 (56.7)
Synchronous local and distant relapse	4 (13.3)

PALN, para-aortic lymph node; SCLN, supra-clavicular lymph node.

Table 2

Univariate analysis of potential risk factors for patients with persistent or recurrent disease, n

Clinical data	Recurrence group (n=30)	Control group (n=35)	χ²	P
Age (years)			0.032	0.857
≤35	3 (10.0)	2 (5.7)
>35	27 (90.0)	33 (94.3)
Stage			2.681	0.262
IB	3 (10.0)	1 (2.9)
II	18 (60.0)	27 (77.1)
III	9 (30.0)	7 (20.0)
Tumor size (cm)			0.707	0.401
≤4	21 (70.0)	21 (60.0)
>4	9 (30.0)	14 (40.0)
Lymph node			19.726	<0.001
Positive	20 (66.7)	5 (16.7)
Negative	10 (33.3)	30 (83.3)
SCCAg (ng/mL)			7.05	0.005
≤10	16 (53.3)	7 (20.0)
>10	14 (46.6)	28 (80.0)
Radiation time (d)			0	1
≤56	26 (86.7)	31 (88.6)
>56	4 (13.3)	4 (11.4)
Radiation dose (Gy)			—	0.495
≤86	30 (100)	33 (94.3)
<86	0 (0)	2 (5.7)
Cycles of chemotherapy			0.372	0.542
≤4	24 (80.0)	31 (88.6)
<4	6 (20.0)	4 (11.4)