[HTML][HTML] Prognostic significance of grade of malignancy based on histopathological differentiation and Ki-67 in pancreatic ductal adenocarcinoma

Y Liang, G Sheng, Y Guo, Y Zou, H Guo… - Cancer Biology & …, 2024 - cancerbiomed.org
Objective: Tumor cell malignancy is indicated by histopathological differentiation and cell
proliferation. Ki-67, an indicator of cellular proliferation, has been used for tumor grading …

Prognostic impact of Ki-67 proliferative index in resectable pancreatic ductal adenocarcinoma

I Pergolini, S Crippa, M Pagnanelli, G Belfiori… - BJS open, 2019 - academic.oup.com
Background Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease
characterized by complex biological features and poor prognosis. A prognostic stratification …

[HTML][HTML] Combined utility of Ki-67 index and tumor grade to stratify patients with pancreatic ductal adenocarcinoma who underwent upfront surgery

B Li, X Yin, X Ding, G Zhang, H Jiang, C Chen, S Guo… - BMC surgery, 2023 - Springer
Objective To investigate the prognostic prediction of a new indicator, combined by tumor
grade and Ki-67, in patients with resected pancreatic ductal adenocarcinoma (PDAC) …

[PDF][PDF] A new staging system for postoperative prognostication in pancreatic ductal adenocarcinoma

Y Liang, J Cui, F Ding, Y Zou, H Guo, Q Man, S Chang… - Iscience, 2023 - cell.com
The current TNM staging system for pancreatic ductal adenocarcinoma (PDAC) has revised
the definitions of T and N categories as well as stage groups. However, studies validating …

Impact of tumor grade on pancreatic cancer prognosis: validation of a novel TNMG staging system

MM Rochefort, JS Ankeny, BE Kadera… - Annals of surgical …, 2013 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) patients demonstrate highly
variable survival within each stage of the American Joint Committee on Cancer (AJCC) …

Validation of a proposed tumor regression grading scheme for pancreatic ductal adenocarcinoma after neoadjuvant therapy as a prognostic indicator for survival

SM Lee, MHG Katz, L Liu, M Sundar… - The American journal …, 2016 - journals.lww.com
Neoadjuvant therapy has been increasingly used to treat patients with potentially resectable
pancreatic ductal adenocarcinoma (PDAC). Although the College of American Pathologists …

The grade of pancreatic ductal carcinoma is an independent prognostic factor and is superior to the immunohistochemical assessment of proliferation

J Lüttges, S Schemm, I Vogel… - The Journal of …, 2000 - Wiley Online Library
Tumour grade is one of the prognostic factors in pancreatic ductal adenocarcinoma, but its
value is controversial. In this study, the predictive value and the reproducibility of the WHO …

[HTML][HTML] Equipping the American Joint Committee on cancer staging for resectable pancreatic ductal adenocarcinoma with tumor grade: A novel staging system

H Ren, CR Wu, GT Qiu, LP Zhang, S Aimaiti… - Journal of …, 2020 - hindawi.com
Background. The 8th American Joint Committee on Cancer (AJCC) staging system for
pancreatic ductal adenocarcinoma (PDAC) outperforms its previous version in …

Prognostic value of histological grading in ductal adenocarcinoma of the pancreas: Klöppel vs TNM grading

PC Giulianotti, U Boggi, G Fornaciari, J Bruno… - International journal of …, 1995 - Springer
A new histological grading system with prognostic correlation for pancreatic cancer was
proposed by Klöppel et al. in 1985. Histological sections from 60 ductal adenocarcinomas …

Systematic review of immunohistochemical biomarkers to identify prognostic subgroups of patients with pancreatic cancer

D Ansari, A Rosendahl, J Elebro… - Journal of British …, 2011 - academic.oup.com
Background Pancreatic ductal adenocarcinoma (PDAC) carries a dismal prognosis. There is
a need to identify prognostic subtypes of PDAC to predict clinical and therapeutic outcomes …