Objective: We aimed to directly compare the estimated effects of adherence to a healthy
lifestyle with those of risk predisposition according to known genetic variants affecting …

Background & Aims The combined effects of healthy lifestyle factors on colorectal cancer
(CRC) risk are unclear. We aimed to develop a healthy lifestyle score, to investigate the joint …

Background: Genetic factors increase the individual risk of colorectal cancer (CRC);
however, the extent to which a healthy lifestyle can offset increased genetic risk is unknown …

Background Both genetic and lifestyle factors play an etiologic role in colorectal cancer
(CRC). Objectives We evaluated potential gene–environment interactions in CRC risk …

Background Excess body weight, physical activity, smoking, alcohol consumption and
certain dietary factors are individually related to colorectal cancer (CRC) risk; however, little …

Purpose Both genetic and lifestyle factors contribute to the risk of colorectal cancer, but each
individual factor has a limited effect. Therefore, we investigated the association between …

It has been suggested that, for a substantial proportion of “sporadic” colorectal cancers
(CRCs), inheritance determines individual susceptibility and that lifestyle determines which …

The objective of this study was to identify distinct clusters of individuals that exhibit unique
patterns of modifiable lifestyle-related behaviours and to determine how these patterns are …

Purpose This study investigated the utility of modeling modifiable lifestyle risk factors in
addition to genetic variation in colorectal cancer (CRC) screening/prevention. Methods We …

Background This study aimed to explore the potential interaction between dietary intake and
genetics on incident colorectal cancer (CRC) and whether adherence to healthy dietary …