[HTML][HTML] Deep-learning methods for unveiling large-scale single-cell transcriptomes

X Shen, X Li - Cancer Biology & Medicine, 2023 - ncbi.nlm.nih.gov
The rapidly evolving realm of single-cell transcriptomics offers vital new perspectives into the
understanding of intra-and inter-cellular molecular dynamics governing development …

[HTML][HTML] Deep learning applications in single-cell genomics and transcriptomics data analysis

N Erfanian, AA Heydari, AM Feriz, P Iañez… - Biomedicine & …, 2023 - Elsevier
Traditional bulk sequencing methods are limited to measuring the average signal in a group
of cells, potentially masking heterogeneity, and rare populations. The single-cell resolution …

[HTML][HTML] Deep learning analysis of single‐cell data in empowering clinical implementation

A Ma, J Wang, D Xu, Q Ma - Clinical and Translational Medicine, 2022 - ncbi.nlm.nih.gov
Recent advances in single-cell sequencing technologies enable the characterization of
cellular heterogeneity and biological processes in complex diseases. This provides …

bigSCale: an analytical framework for big-scale single-cell data

G Iacono, E Mereu, A Guillaumet-Adkins… - Genome …, 2018 - genome.cshlp.org
Single-cell RNA sequencing (scRNA-seq) has significantly deepened our insights into
complex tissues, with the latest techniques capable of processing tens of thousands of cells …

[HTML][HTML] Deep learning shapes single-cell data analysis

Q Ma, D Xu - Nature Reviews Molecular Cell Biology, 2022 - nature.com
Deep learning has tremendous potential in single-cell data analyses, but numerous
challenges and possible new developments remain to be explored. In this commentary, we …

[HTML][HTML] A hitchhiker's guide to single-cell transcriptomics and data analysis pipelines

R Nayak, Y Hasija - Genomics, 2021 - Elsevier
Single-cell transcriptomics (SCT) is a tour de force in the era of big omics data that has led to
the accumulation of massive cellular transcription data at an astounding resolution of single …

[HTML][HTML] Single cell insights into Cancer transcriptomes: a five-part single-cell RNAseq case study lesson

LA Samsa, M Eslinger, A Kleinschmit, A Solem… - 2021 - qubeshub.org
There is a growing need for integration of “Big Data” into undergraduate biology curricula.
Transcriptomics is one venue to examine biology from an informatics perspective. RNA …

Methods towards precision bioinformatics in single cell era

Y Cao - 2023 - ses.library.usyd.edu.au
Single-cell technology offers unprecedented insight into the molecular landscape of
individual cell and is transforming precision medicine. Key to the effective use of single-cell …

[HTML][HTML] Advances in single-cell RNA sequencing and its applications in cancer research

S Zhu, T Qing, Y Zheng, L Jin, L Shi - Oncotarget, 2017 - ncbi.nlm.nih.gov
Unlike population-level approaches, single-cell RNA sequencing enables transcriptomic
analysis of an individual cell. Through the combination of high-throughput sequencing and …

Deep learning tackles single-cell analysis—a survey of deep learning for scRNA-seq analysis

M Flores, Z Liu, T Zhang, MM Hasib… - Briefings in …, 2022 - academic.oup.com
Since its selection as the method of the year in 2013, single-cell technologies have become
mature enough to provide answers to complex research questions. With the growth of single …