Multi-targeted therapies in non-small cell lung cancer

K Wang, J Wei - Clinical Oncology and Cancer Research, 2011 - Springer
Current treatment modalities provide limited improvement in the natural course of lung
cancer, and prognosis remains poor. Lung cancer is a malignancy with great molecular …

Multitargeted inhibitors in lung cancer: new clinical data

J Bar, RS Herbst, A Onn - Clinical lung cancer, 2008 - Elsevier
Novel therapies have been added to the treatment arsenal of physicians treating lung
cancer in recent years. Most promising are agents that target the major pathways involved in …

Targeted therapies for non-small cell lung cancer

GS Papaetis, C Roussos… - Current pharmaceutical …, 2007 - ingentaconnect.com
Conventional therapy for non-small cell lung cancer (NSCLC) has reached a plateau in
increasing patient survival and overall prognosis still remains dismal. Advances in the …

Targeted therapy developments in the treatment of non-small cell lung cancer: a promising but long and winding road

C Gridelli - Current Opinion in Oncology, 2008 - journals.lww.com
Lung cancer remains the leading cause of malignancyrelated mortality worldwide with over
a million cases diagnosed yearly. Non-small cell lung cancer (NSCLC) accounts for more …

New targets and new treatments in non-small cell lung cancer

BE Johnson - European Journal of Cancer Supplements, 2004 - Elsevier
New agents directed against molecular targets have now been tested in large prospectively
randomized clinical trials for patients with untreated advanced non-small cell lung cancer …

Targeted therapies for advanced non-small-cell lung cancer: current status and future implications

A Custodio, M Méndez, M Provencio - Cancer treatment reviews, 2012 - Elsevier
Lung cancer remains the leading cause of malignancy-related mortality worldwide, with over
one million cases diagnosed yearly. Non-small-cell lung cancer (NSCLC) accounts for> …

Non-small-cell lung cancer: targeted therapies

A Rossi - Clinical Practice, 2009 - search.proquest.com
The major progresses in understanding cancer biology and the mechanism of oncogenesis
have allowed the development of several potential molecular target drugs for cancer …

The potential role of new targeted therapies in the treatment of advanced non-small-cell lung cancer.

F Casaluce, A Sgambato, P Maione, A Rossi, C Ferrara… - 2013 - cabidigitallibrary.org
Platinum-based doublet chemotherapy is the standard treatment for advanced non-small-
cell lung cancer, with a median survival and 1-year survival of 8-10 weeks and 30-40 …

Advance on targeted therapy for the treatment of non-small cell lung cancer

Z LI, S LU - Cancer Research and Clinic, 2010 - pesquisa.bvsalud.org
Recent progress in molecular biology has enabled us to better understand the molecular
mechanism underlying pathogenesis of human malignancy including lung cancer, the …

Targeted therapies and non-small-cell lung cancer: work in progress?

C Gridelli - Current Opinion in Oncology, 2006 - journals.lww.com
The outcome of treatments for non-small-cell lung cancer (NSCLC) can still be considered to
be disappointing [1]. Advances in knowledge about tumour biology and mechanisms of …