Neutrophils, a crucial component of the innate immune system, are the most abundant bone
marrow-derived eukaryotic cell in human blood. The functional importance of neutrophils is …

Introduction: Neutrophils or polymorphonuclear cells (PMNs) account for a considerable
portion of the tumor immune stroma. Emerging single-cell transcriptomic analyses have …

Neutrophils—once considered as simple killers of pathogens and unexciting for cancer
research—are now acknowledged for their role in the process of tumorigenesis. Neutrophils …

The role and importance of neutrophils in cancer has become increasingly apparent over
the past decade. Neutrophils accumulate in the peripheral blood of patients with cancer …

Neutrophils, the most abundant circulating leukocytes in human, play an indispensable role
in the innate immune response to microbial infections. However, the contribution of tumor …

In recent years, the role of neutrophils in cancer biology has been a matter of increasing
interest. Many patients with advanced cancer show high levels of neutrophilia, tumor …

Neutrophils are the most abundant circulating leukocytes in humans. Neutrophil infiltration
into tumor tissues has long been observed but its roles have been ignored due to the …

Neutrophils play a key role in defence against infection and in the activation and regulation
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …

Neutrophils have been extensively described in the pathophysiology of autoimmune and
infectious diseases. Accumulating evidence also suggests the important role of neutrophils …

Purpose Neutrophils act as a non-negligible regulator in the initiation and progression of
malignancies, playing bifacial roles in the process. Thus, to understand the heterogeneity of …