[HTML][HTML] Sex-determining region Y box-containing genes: regulators and biomarkers in gynecological cancers

J Hu, K Li, Z Li, C Gao, F Guo, Y Wang… - Cancer Biology & …, 2019 - ncbi.nlm.nih.gov
Sex-determining region Y box-containing genes are transcription factors with roles in
multiple biological processes, including cell differentiation, proliferation, and apoptosis. Sex …

Sex-determining region Y-box 2 expression predicts poor prognosis in human ovarian carcinoma

J Zhang, DY Chang, I Mercado-Uribe, J Liu - Human pathology, 2012 - Elsevier
Sex-determining region Y-box 2 is proposed to be a key transcription factor in embryonic
stem cells. The known roles of sex-determining region Y-box 2 in development and cell …

Sex-determining region Y-box 2 amplification in preneoplastic squamous lesions of the lung

F Schneider, A Luvison, K Cieply, S Dacic - Human Pathology, 2013 - Elsevier
Sex-determining region Y-box 2 gene at 3q26. 33 has been identified as oncogene in
squamous cell carcinoma occurring at different anatomical sites including the lung. Sex …

X-and Y-linked chromatin-modifying genes as regulators of sex-specific cancer incidence and prognosis

R Tricarico, E Nicolas, MJ Hall, EA Golemis - Clinical Cancer Research, 2020 - AACR
Biological sex profoundly conditions organismal development and physiology, imposing
wide-ranging effects on cell signaling, metabolism, and immune response. These effects …

Correlation of sex‐determining region Y‐box 30 with tumor characteristics and its prognostic value in breast cancer

H Peng, Y Luo, J Wu, W Yin - Journal of Clinical Laboratory …, 2020 - Wiley Online Library
Objective Sex‐determining region Y‐box 30 (SOX30) suppresses progression of several
cancers, whereas its role in breast cancer is unclear. Therefore, we aimed to determine the …

[HTML][HTML] Y chromosome is moving out of sex determination shadow

R Heydari, Z Jangravi, S Maleknia, M Seresht-Ahmadi… - Cell & Bioscience, 2022 - Springer
Although sex hormones play a key role in sex differences in susceptibility, severity,
outcomes, and response to therapy of different diseases, sex chromosomes are also …

Co-expression of Y box-binding protein-1 and P-glycoprotein as a prognostic marker for survival in epithelial ovarian cancer

X Huang, K Ushijima, K Komai, Y Takemoto… - Gynecologic …, 2004 - Elsevier
Objectives. This study aimed to observe the expressions of Y box-binding protein-1 (YB-1)
and P-glycoprotein (P-gp) in primary ovarian tumor and to determine whether they act as …

The Y chromosome as a risk factor

A Dart - Nature Reviews Cancer, 2023 - nature.com
The Y chromosome as a risk factor | Nature Reviews Cancer Skip to main content Thank you
for visiting nature.com. You are using a browser version with limited support for CSS. To …

A new role for the Y chromosome in cancer growth and immunotherapy response

A Fenner - Nature Reviews Urology, 2023 - nature.com
Despite evidence that loss of the Y chromosome (LOY) occurs in up to 40% of bladder
cancers, the biological significance of this event has been elusive. However, new data …

Novel Perspective: Focusing on the X Chromosome in Reproductive Cancers: ESSAY

DJ Liao, Q Du, BW Yu, D Grignon… - Cancer investigation, 2003 - Taylor & Francis
In an XX female, one of the two X chromosomes has been inactivated during early
embryonic life to achieve a compensation of X-linked gene products between males and …