Biobanks bridge the gap between basic and translational research. Traditional cancer
biobanks typically contain normal and tumor tissues, and matched blood. However …

Simple Summary Despite significant strides in multimodal therapy, cancers still rank within
the first three causes of death especially in industrial nations. A lack of individualized …

Organoids are three-dimensional culture systems generated from embryonic stem cells,
induced pluripotent stem cells, and adult stem cells. They are capable of cell proliferation …

The recent advances in in vitro 3D culture technologies, such as organoids, have opened
new avenues for the development of novel, more physiological human cancer models. Such …

Cancer harbors variable heterogeneity and plasticity. Thus far, our comprehension is greatly
based on cell lines, organoids, and patient-derived tumor xenografts (PDTXs). Organoids …

Organoids are a new type of 3D model for tumor research, which makes up for the
shortcomings of cell lines and xenograft models, and promotes the development of …

Tumor organoids are 3D cultures of cancer cells that can be derived on an individual patient
basis with a high success rate. This creates opportunities to build large biobanks with …

Organoid cultures have emerged as powerful model systems accelerating discoveries in
cellular and cancer biology. These three-dimensional cultures are amenable to diverse …

Tumor models have created new avenues for personalized medicine and drug
development. A new culture model derived from a three-dimensional system, the tumor …

During the past decade, the three-dimensional organoid technology has sprung up and
become more and more popular among researchers. Organoids are the miniatures of in vivo …