[HTML][HTML] Mechanistic considerations for the use of monoclonal antibodies for cancer therapy

PM Glassman, JP Balthasar - Cancer biology & medicine, 2014 - ncbi.nlm.nih.gov
Since the approval of rituximab in 1997, monoclonal antibodies (mAbs) have become an
increasingly important component of therapeutic regimens in oncology. The success of …

[HTML][HTML] Combination radioimmunotherapy strategies for solid tumors

J Zaheer, H Kim, YJ Lee, JS Kim, SM Lim - International Journal of …, 2019 - mdpi.com
Combination radioimmunotherapy is an emerging approach for the treatment of solid tumors
where radio immunotherapy alone has proven to be reasonably ineffective …

Prospective evaluation of cetuximab-mediated antibody-dependent cell cytotoxicity in metastatic colorectal cancer patients predicts treatment efficacy

AM Trotta, A Ottaiano, C Romano, G Nasti… - Cancer immunology …, 2016 - AACR
Cetuximab is a monoclonal antibody to the EGFR that induces antibody-dependent cell
cytotoxicity (ADCC) through Fcγ receptors on immune cells. Although SNPs in genes …

A cetuximab-mediated suicide system in chimeric antigen receptor–modified hematopoietic stem cells for cancer therapy

RL Kao, LC Truscott, TT Chiou, W Tsai, AM Wu… - Human gene …, 2019 - liebertpub.com
Using gene modification of hematopoietic stem cells (HSC) to create persistent generation of
multilineage immune effectors to target cancer cells directly is proposed. Gene-modified …

Study protocol: phase II study to evaluate the effect of cetuximab monotherapy after immunotherapy with PD-1 inhibitors in patients with head and neck squamous cell …

KM Burcher, CH Bloomer, E Gavrila… - Therapeutic …, 2024 - journals.sagepub.com
Background: Immunotherapy with programmed death receptor-1 (PD-1) inhibitors, as a
single agent or in combination with chemotherapy, is the standard first-line treatment for …

[HTML][HTML] Peripheral white blood cell subsets in metastatic colorectal cancer patients treated with cetuximab: the potential clinical relevance

IZ Matić, B Kolundžija, A Damjanović, J Spasić… - Frontiers in …, 2018 - frontiersin.org
It was demonstrated that cetuximab-induced tumor regression is based on the effects
exerted by immune cells included mainly in the innate immune response. Therefore, the …

Relación entre la expresión proteínas inhibidoras de complemento y la eficacia de anticuerpos terapéuticos en cáncer colorrectal

SÁ Lorenzo, NS Jazmín - Revista de Farmacología, 2022 - revistafarmacologia.mx
El cáncer colorrectal ocupa el segundo lugar en mortalidad a nivel nacional y el tercero en
incidencia a nivel mundial. Su tratamiento involucra cirugía, radioterapia y combinaciones …

Machbarkeit und Sicherheit einer kombinierten Therapie mittels transarterieller Chemoembolisation mit Irinotecan beladenen Mikrosphären (DEBIRI-TACE) und CT …

MA Meddeb - 2022 - refubium.fu-berlin.de
Das kolorektale Karzinom ist die dritthäufigste maligne Erkrankung weltweit und die
Inzidenz zeigt eine steigende Tendenz. Hepatisch metastasierte kolorektale Karzinome …

Anti-tumor agent containing immunomodulator, and antitumor effect potentiator

N Suzuki - US Patent 11,612,653, 2023 - Google Patents
US11612653B2 - Anti-tumor agent containing immunomodulator, and antitumor effect
potentiator - Google Patents US11612653B2 - Anti-tumor agent containing …

[PDF][PDF] Targeting p53 in anticancer therapy: Searching for new small molecule activators.

BS da Silva - 2018 - repositorio-aberto.up.pt
This work was performed at the Laboratory of Microbiology of Biological Sciences
Department of Faculty of Pharmacy of University of Porto, in collaboration with Laboratory of …