De novo design of inhibitors of DNA methyltransferase 1: A critical comparison of ligand-and structure-based approaches

DL Prado-Romero, FI Saldivar-González, I López-Mata… - 2024 - chemrxiv.org
Designing and developing inhibitors against the epigenetic target DNA methyltransferase
(DNMT) is an attractive strategy in epigenetic drug discovery. DNMT1 is one of the …