Spheroids and organoids are important novel players in medical and life science research.
They are gradually replacing two-dimensional (2D) cell cultures. Indeed, three-dimensional …

Breast cancer is the most common cancer in women and responsible for multiple deaths
worldwide. 3D cancer models enable a better representation of tumor physiology than the …

Organoids are established through in vitro 3D culture, and they can mimic the structure and
physiological functions of organs or tissues in vivo. Organoids have attracted much attention …

Background Gynecological cancers encompass all uncontrolled and aberrant cell growth in
the female reproductive system, therapeutic interventions are constantly evolving, but there …

Objective: Organoids are a powerful tool with broad application prospects in biomedicine.
Notably, they provide alternatives to animal models for testing potential drugs before clinical …

Mouse models of disease play a pivotal role at all stages of cancer drug development. Cell-
line derived subcutaneous tumour models are predominant in early drug discovery, but …

The advancement of CRISPR mediated gene engineering provides an opportunity to
improve upon preclinical human cell line models of cancer predisposing syndromes. This …

Breast cancer stands as the most prevalent and heterogeneous malignancy affecting
women globally, posing a substantial health concern. Enhanced comprehension of tumor …

Gastrointestinal cancers are a public health problem that threatens the lives of human being.
A good experimental model is a powerful tool to promote the uncovering pathogenesis and …

Several therapies to improve the management of lymphoma are currently being
investigated, necessitating the development of new biomarkers. However, this requires high …