[HTML][HTML] Circular RNAs: New layer of complexity evading breast cancer heterogeneity

A Dawoud, ZI Zakaria, HH Rashwan… - Non-Coding RNA …, 2023 - Elsevier
Advances in high-throughput sequencing techniques and bioinformatic analysis have
refuted the “junk” RNA hypothesis that was claimed against non-coding RNAs (ncRNAs) …

[HTML][HTML] A Circular RNAs: Emerging roles and new insights in human cancers

Z He, Q Zhu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Circular RNAs (circRNAs) are single-stranded, covalently closed RNA molecules formed by
mRNA exon back-splicing. Although the circRNA functions remain largely unknown, their …

[HTML][HTML] Circular RNAs: implications of signaling pathways and bioinformatics in human cancer

F Hu, Y Peng, X Fan, X Zhang, Z Jin - Cancer Biology & Medicine, 2023 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) form a class of endogenous single-stranded RNA transcripts that
are widely expressed in eukaryotic cells. These RNAs mediate post-transcriptional control of …

[HTML][HTML] circROBO1 promotes prostate cancer growth and enzalutamide resistance via accelerating glycolysis

Z Zhou, J Qin, C Song, T Wu, Q Quan, Y Zhang… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background and aim: As non-coding RNAs, circular RNAs (circRNAs) contribute to the
progression of malignancies by regulating various biological processes. In prostate cancer …

CircEGFR reduces the sensitivity of pirarubicin and regulates the malignant progression of triple-negative breast cancer via the miR-1299/EGFR axis

J Ma, C Chen, Z Fan, Y Zhang, J Ji, D Wei… - International Journal of …, 2023 - Elsevier
Circular RNAs (circRNAs) have been found to be involved in cancer progression and
chemotherapy sensitivity. However, the biological function of circRNAs in triple-negative …

FOXQ1 inhibits breast cancer ferroptosis and progression via the circ_0000643/miR-153/SLC7A11 axis

X Huang, J Wu, Y Wang, Z Xian, J Li, N Qiu… - Experimental cell research, 2023 - Elsevier
Dysregulation of ferroptosis is involved in breast cancer progression and therapeutic
responses. Inducing ferroptosis can be a potential therapeutic strategy for breast cancer …

CircANKRD17 promotes glycolysis by inhibiting miR‐143 in breast cancer cells

H Chen, LF Zhang, L Zhang, Y Miao… - Journal of Cellular …, 2023 - Wiley Online Library
Glucose metabolic reprogramming, known as the Warburg effect, is one of the metabolic
hallmarks of tumor cells. Cancer cells preferentially metabolize glucose by glycolysis rather …

[HTML][HTML] Circular RNA: A promising new star of vaccine

J Xie, F Ye, X Deng, Y Tang, JY Liang… - Journal of …, 2023 - degruyter.com
Circular RNAs (circRNAs) are a class of single-stranded RNAs with covalently closed
structures. Owing to their not having 3'or 5'ends, circRNAs are highly durable and …

[HTML][HTML] Non-Coding RNAs in Oral Cancer: Emerging Roles and Clinical Applications

S Dey, B Biswas, A Manoj Appadan, J Shah, JK Pal… - Cancers, 2023 - mdpi.com
Simple Summary Oral cancer (OC) is one of the most prevalent cancers in the world. Despite
improvements in therapies, OC still has a poor survival rate of about 50%, with metastasis …

[HTML][HTML] Methotrexate alters the expression of microrna in fibroblast-like synovial cells in rheumatoid arthritis

N Iwamoto, K Furukawa, Y Endo, T Shimizu… - International Journal of …, 2021 - mdpi.com
We aimed to investigate the effect of methotrexate (MTX) on microRNA modulation in
rheumatoid arthritis fibroblast-like synovial cells (RA-FLS). RA-FLS were treated with MTX …