Amivantamab plus Chemotherapy in NSCLC with EGFR Exon 20 Insertions

C Zhou, KJ Tang, BC Cho, B Liu… - … England Journal of …, 2023 - Mass Medical Soc
Background Amivantamab has been approved for the treatment of patients with advanced
non–small-cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 …

Perspectives for the use of fucoidans in clinical oncology

MV Kiselevskiy, NY Anisimova… - International Journal of …, 2022 - mdpi.com
Fucoidans are natural sulfated polysaccharides that have a wide range of biological
functions and are regarded as promising antitumor agents. The activity of various fucoidans …

Elevated Risk of Fluoropyrimidine-Associated Toxicity in European Patients with DPYD Genetic Polymorphism: A Systematic Review and Meta-Analysis

W Kim, YA Cho, DC Kim, KE Lee - Journal of Personalized Medicine, 2022 - mdpi.com
Background: Fluoropyrimidine is widely used owing to its clinical efficacy, however, patients
with dihydropyrimidine dehydrogenase (DPD) deficiency can experience fluoropyrimidine …

Chondroitin sulfate and fucosylated chondroitin sulfate as stimulators of hematopoiesis in cyclophosphamide-induced mice

NE Ustyuzhanina, NY Anisimova, MI Bilan… - Pharmaceuticals, 2021 - mdpi.com
The immunosuppression and inhibition of hematopoiesis are considered to be reasons for
the development of complications after intensive chemotherapy and allogeneic …

Chemotherapy-induced neutropenia elicits metastasis formation in mice by promoting proliferation of disseminated tumor cells

M Russo, N Panini, P Fabbrizio, L Formenti… - …, 2023 - Taylor & Francis
Chemotherapy is the standard of care for most malignancies. Its tumor debulking effect in
adjuvant or neoadjuvant settings is unquestionable, although secondary effects have been …

[HTML][HTML] Investigation of chemoresistance to first-line chemotherapy and its possible association with autophagy in high-risk neuroblastoma

T Chen, C Zeng, Z Li, J Wang, F Sun, J Huang… - Frontiers in …, 2022 - frontiersin.org
High-risk neuroblastoma (NB) is sensitive to chemotherapy but susceptible to
chemoresistance. In this study, we aimed to analyze the incidence of chemoresistance in …

The Efficacy of Nanoparticle Delivery to Hypoxic Solid Tumors by ciRGD Co‐Administration Depends on Neuropilin‐1 and Neutrophil Levels

M Izci, C Maksoudian, F Gonçalves… - Advanced …, 2023 - Wiley Online Library
The ability to improve nanoparticle delivery to solid tumors is an actively studied domain,
where various mechanisms are looked into. In previous work, the authors have looked into …

Hematopoietic Effects of Angelica gigas Nakai Extract on Cyclophosphamide-Induced Myelosuppression

M Kang, S Park, Y Chung, JO Lim, JS Kang, JH Park - Plants, 2022 - mdpi.com
Myelosuppression is a major adverse effect of chemotherapy. With the increasing number of
cancer patients worldwide, there is a growing interest in therapeutic approaches that reduce …

Management of adult patients with haematological malignancies in critical care

S Fizza Haider, R Sloss, S Jhanji, E Nicholson… - …, 2023 - Wiley Online Library
There are a diverse range of haematological malignancies with varying clinical
presentations and prognoses. Patients with haematological malignancy may require …

[HTML][HTML] Safety and tolerability of weekly genexol-pm, a cremophor-free polymeric micelle formulation of paclitaxel, with carboplatin in gynecologic cancer: a phase i …

SH Nam, SW Lee, YJ Lee, YM Kim - Cancer Research and …, 2023 - ncbi.nlm.nih.gov
Purpose This phase I study was conducted to determine the maximum tolerated dose and
the recommended phase II dose of weekly administered Genexol-PM combined with …