Immunotherapy of glioblastoma: Recent advances and future prospects

B Yuan, G Wang, X Tang, A Tong… - Human vaccines & …, 2022 - Taylor & Francis
Glioblastoma (GBM) stands out as the most common, aggressive form of primary malignant
brain tumor conferring a devastatingly poor prognosis. Despite aggressive standard-of-care …

[HTML][HTML] Decipher the glioblastoma microenvironment: the first milestone for new groundbreaking therapeutic strategies

GN Fanelli, D Grassini, V Ortenzi, F Pasqualetti… - Genes, 2021 - mdpi.com
Glioblastoma (GBM) is the most common primary malignant brain tumour in adults. Despite
the combination of novel therapeutical approaches, it remains a deadly malignancy with an …

[HTML][HTML] Glioblastoma immunotherapy: A systematic review of the present strategies and prospects for advancements

E Agosti, M Zeppieri, L De Maria, C Tedeschi… - International Journal of …, 2023 - mdpi.com
Glioblastoma (GBM) is characterized by aggressive growth and high rates of recurrence.
Despite the advancements in conventional therapies, the prognosis for GBM patients …

[HTML][HTML] ARPC5 acts as a potential prognostic biomarker that is associated with cell proliferation, migration and immune infiltrate in gliomas

Y Ming, C Luo, B Ji, J Cheng - Bmc Cancer, 2023 - Springer
Background Gliomas are the most common malignant brain tumors, with powerful
invasiveness and an undesirable prognosis. Actin related protein 2/3 complex subunit 5 …

[HTML][HTML] Chimeric Antigen Receptor T Cells in Glioblastoma—Current Concepts and Promising Future

R Kringel, K Lamszus, M Mohme - Cells, 2023 - mdpi.com
Glioblastoma (GBM) is a highly aggressive primary brain tumor that is largely refractory to
treatment and, therefore, invariably relapses. GBM patients have a median overall survival of …

[HTML][HTML] Development and validation of prognostic model based on the analysis of autophagy-related genes in colon cancer

Y Wang, K Lin, T Xu, L Wang, L Fu, G Zhang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Background: Autophagy, a process of self-digestion, is closely related to multiple biological
processes of colon cancer. This study aimed to construct and evaluate prognostic signature …

Cancer stem cells in brain tumors: From origin to clinical implications

S Lin, K Li, L Qi - MedComm, 2023 - Wiley Online Library
Malignant brain tumors are highly heterogeneous tumors with a poor prognosis and a high
morbidity and mortality rate in both children and adults. The cancer stem cell (CSC, also …

[HTML][HTML] Identification of an N6-methyladenosine (m6A)-related signature associated with clinical prognosis, immune response, and chemotherapy in primary …

Z Cai, J Zhang, Z Liu, J Su, J Xu, Z Li… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background N6-methyladenosine (m6A) RNA methylation regulators play crucial role in
tumorigenicity and progression. However, their biological significance in primary …

[HTML][HTML] PTPN1 is a prognostic biomarker related to cancer immunity and drug sensitivity: from pan-cancer analysis to validation in breast cancer

R Zhao, S Chen, W Cui, C Xie, A Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Protein tyrosine phosphatase non-receptor type 1 (PTPN1), a member of the
protein tyrosine phosphatase superfamily, has been identified as an oncogene and …

[HTML][HTML] Tumor immune microenvironment landscape in glioma identifies a prognostic and immunotherapeutic signature

C Zhang, L Guo, Z Su, N Luo, Y Tan, P Xu… - Frontiers in Cell and …, 2021 - frontiersin.org
The tumor immune microenvironment (TIME) has been recognized to be associated with
sensitivity to immunotherapy and patient prognosis. Recent research demonstrates that …