Sun exposure is a major environmental risk factor for skin cancers and is also an important
source of vitamin D. However, while experimental evidence suggests that vitamin D may …

Skin cancer is the most frequent type of cancer in humans. While exposure to solar radiation
is the most widely known and relevant causal factor, the different degrees of individual risk …

Increasing scientific evidence supports the link between vitamin D and cancer risk. The
active metabolite 1, 25 (OH) 2D exerts its activity by binding to the vitamin D receptor (VDR) …

Sun exposure is the main risk factor for cutaneous malignant melanoma (CMM). However,
the UV-related pathogenetic mechanisms leading to CMM are far to be fully elucidated. In …

Background/Aim: Increasing evidence indicates a relevance of the vitamin D endocrine
system for pathogenesis of malignant melanoma. We performed a systematic review and …

Vitamin D is a precursor for secosteroidal hormones, which demonstrate pleiotropic
biological activities, including the regulation of growth and the differentiation of normal and …

Multiple myeloma (MM) is a plasma cell malignancy frequently accompanied with skeletal co-
morbidity. Vitamin D (1, 25 (OH) 2 D) is an important mediator of skeletal homeostasis that …

Simple Summary The impact of obesity on melanoma has rarely been researched.
Incidence of obesity is rapidly growing and melanoma is one of the most prevalent types of …

Gastric cancer is the second cause of cancer‐related mortality and the fourth most common
cancers worldwide. Owing to the immune modulatory effect of vitamin D in the body, the role …

Adalimumab (ADA) is a human anti-tumor necrosis factor (TNF-α) monoclonal antibody used
in inflammatory bowel diseases, such as Crohn's disease (CD). Vitamin-D (VD) is important …