Mechanisms of apoptosis modulation by curcumin: Implications for cancer therapy
K Mortezaee, E Salehi… - Journal of cellular …, 2019 - Wiley Online Library
Cancer incidences are growing and cause millions of deaths worldwide. Cancer therapy is
one of the most important challenges in medicine. Improving therapeutic outcomes from …
one of the most important challenges in medicine. Improving therapeutic outcomes from …
Pathophysiological implications of neuroinflammation mediated HPA axis dysregulation in the prognosis of cancer and depression
Cancer patients are more likely to develop depressive symptoms and show a poor
prognosis compared to the normal healthy individuals. Cancer occurrence and the …
prognosis compared to the normal healthy individuals. Cancer occurrence and the …
[HTML][HTML] IKKβ inhibition attenuates epithelial mesenchymal transition of human stem cell-derived retinal pigment epithelium
SR Sripathi, MW Hu, RC Turaga, R Mikeasky… - Cells, 2023 - mdpi.com
Epithelial-mesenchymal transition (EMT), which is well known for its role in embryonic
development, malignant transformation, and tumor progression, has also been implicated in …
development, malignant transformation, and tumor progression, has also been implicated in …
[HTML][HTML] NF-κB sub-pathways and HIV cure: A revisit
LM Wong, G Jiang - EBioMedicine, 2021 - thelancet.com
HIV cure is thwarted by the presence of quiescent yet replication competent HIV-1 (HIV).
Antiretroviral therapy (ART) is unable to eradicate reservoirs, and upon cessation of ART …
Antiretroviral therapy (ART) is unable to eradicate reservoirs, and upon cessation of ART …
[HTML][HTML] β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial–mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB …
K Zou, Z Li, Y Zhang, L Mu, M Chen, R Wang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Radiation therapy is widely used to treat a variety of malignant tumors, including non-small-
cell lung cancer (NSCLC). However, ionizing radiation (IR) paradoxically promotes …
cell lung cancer (NSCLC). However, ionizing radiation (IR) paradoxically promotes …
[HTML][HTML] Mechanisms and perspective treatment of radioresistance in non-small cell lung cancer
T Zhou, LY Zhang, JZ He, ZM Miao, YY Li… - Frontiers in …, 2023 - frontiersin.org
Radiotherapy is the major treatment of non-small cell lung cancer (NSCLC). The
radioresistance and toxicity are the main obstacles that leading to therapeutic failure and …
radioresistance and toxicity are the main obstacles that leading to therapeutic failure and …
'Stemness' and 'senescence'related escape pathways are dose dependent in lung cancer cells surviving post irradiation
A Tsolou, I Lamprou, AO Fortosi, M Liousia… - Life sciences, 2019 - Elsevier
Aims Lung cancer is one of the main causes of cancer-related deaths worldwide and
radiotherapy is a major treatment of choice. However, radioresistance is a main reason for …
radiotherapy is a major treatment of choice. However, radioresistance is a main reason for …
[HTML][HTML] Pentoxifylline sensitizes cisplatin-resistant human cervical cancer cells to cisplatin treatment: involvement of mitochondrial and NF-Kappa B pathways
A Bravo-Cuellar, PC Ortiz-Lazareno… - Frontiers in …, 2020 - frontiersin.org
Background: Cervical cancer continues to be a major public health problem worldwide, and
Cisplatin is used as first-line chemotherapy for this cancer; however, malignant cells …
Cisplatin is used as first-line chemotherapy for this cancer; however, malignant cells …
Decrease in MAP3Ks expression enhances the cell death caused by hyperthermia
A Enomoto, T Fukasawa, H Terunuma… - International Journal …, 2022 - Taylor & Francis
Purpose Hyperthermia is a promising anticancer treatment modality. However, the molecular
mechanism underlying the thermal sensitivity of tumor cells is largely unknown. The aim of …
mechanism underlying the thermal sensitivity of tumor cells is largely unknown. The aim of …
Increased glucose influx and glycogenesis in lung cancer cells surviving after irradiation
A Tsolou, D Koparanis, I Lamprou… - … Journal of Radiation …, 2023 - Taylor & Francis
Purpose Lung cancer is considered as one of the most frequent malignancies worldwide.
Radiotherapy is the main treatment modality applied for locally advanced disease, but …
Radiotherapy is the main treatment modality applied for locally advanced disease, but …