Epigenetic therapy inhibits metastases by disrupting premetastatic niches
Cancer recurrence after surgery remains an unresolved clinical problem 1 , 2 – 3 . Myeloid
cells derived from bone marrow contribute to the formation of the premetastatic …
cells derived from bone marrow contribute to the formation of the premetastatic …
Sintilimab versus placebo in combination with chemotherapy as first line treatment for locally advanced or metastatic oesophageal squamous cell carcinoma (ORIENT …
Z Lu, J Wang, Y Shu, L Liu, L Kong, L Yang, B Wang… - Bmj, 2022 - bmj.com
Objective To evaluate sintilimab versus placebo in combination with chemotherapy (cisplatin
plus paclitaxel or cisplatin plus 5-fluorouracil) as first line treatment of unresectable locally …
plus paclitaxel or cisplatin plus 5-fluorouracil) as first line treatment of unresectable locally …
[HTML][HTML] Tumor copy-number alterations predict response to immune-checkpoint-blockade in gastrointestinal cancer
Z Lu, H Chen, S Li, J Gong, J Li, J Zou… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Despite the great achievements made in immune-checkpoint-blockade (ICB) in
cancer therapy, there are no effective predictive biomarkers in gastrointestinal (GI) cancer. …
cancer therapy, there are no effective predictive biomarkers in gastrointestinal (GI) cancer. …
[HTML][HTML] Early interdisciplinary supportive care in patients with previously untreated metastatic esophagogastric cancer: a phase III randomized controlled trial
Z Lu, Y Fang, C Liu, X Zhang, X Xin, Y He… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
… Provision of study material or patients: Zhihao Lu, Yu Fang, Xiaotian Zhang, Xiaowei Xin,
Yi He, Ying Pang, Yanli Wang, Jun Zhou, Changsong Qi, Jifang Gong, Xicheng Wang, Jian …
Yi He, Ying Pang, Yanli Wang, Jun Zhou, Changsong Qi, Jifang Gong, Xicheng Wang, Jian …
[PDF][PDF] Current status and future perspective of immunotherapy in gastrointestinal cancers
Z Lu, Z Peng, C Liu, Z Wang, Y Wang, X Jiao, J Li… - The Innovation, 2020 - cell.com
Gastrointestinal (GI) cancers represent a major public health problem worldwide. Due to the
late detection and high heterogeneity of GI cancers, traditional treatments, including surgery, …
late detection and high heterogeneity of GI cancers, traditional treatments, including surgery, …
Claudin18. 2-specific CAR T cells in gastrointestinal cancers: phase 1 trial interim results
…, Z Peng, J Zhou, Y Cao, X Zhang, Z Lu, M Lu… - Nature medicine, 2022 - nature.com
Despite success in hematologic malignancies, the treatment landscape of chimeric antigen
receptor (CAR) T cell therapy for solid tumors remains limited. Claudin18.2 (CLDN18.2)-…
receptor (CAR) T cell therapy for solid tumors remains limited. Claudin18.2 (CLDN18.2)-…
The gut microbiome is associated with clinical response to anti–PD-1/PD-L1 immunotherapy in gastrointestinal cancer
…, J Gong, J Li, M Lu, X Wang, J Zhou, ZH Lu… - Cancer Immunology …, 2020 - AACR
We report on a comprehensive analysis of the gut microbiomes of patients with gastrointestinal
(GI) cancer receiving anti–PD-1/PD-L1 treatment. The human gut microbiota has been …
(GI) cancer receiving anti–PD-1/PD-L1 treatment. The human gut microbiota has been …
Pangenome analysis provides insight into the evolution of the orange subfamily and a key gene for citric acid accumulation in citrus fruits
…, S Yang, X Jiang, Z Liu, L Wang, X Wang, S Liu, Z Lu… - Nature Genetics, 2023 - nature.com
The orange subfamily (Aurantioideae) contains several Citrus species cultivated worldwide,
such as sweet orange and lemon. The origin of Citrus species has long been debated and …
such as sweet orange and lemon. The origin of Citrus species has long been debated and …
[HTML][HTML] Pan-Asian adapted ESMO Clinical Practice Guidelines for the management of patients with metastatic gastric cancer: a JSMO–ESMO initiative endorsed by …
…, WIW Zamaniah, WP Yong, KH Yeh, K Kato, Z Lu… - Annals of …, 2019 - Elsevier
The most recent version of the European Society for Medical Oncology (ESMO) Clinical
Practice Guidelines for the diagnosis, treatment and follow-up of gastric cancer (GC) was …
Practice Guidelines for the diagnosis, treatment and follow-up of gastric cancer (GC) was …
Somatic variations led to the selection of acidic and acidless orange cultivars
L Wang, Y Huang, ZA Liu, J He, X Jiang, F He, Z Lu… - Nature Plants, 2021 - nature.com
Somatic variations are a major source of genetic diversification in asexual plants, and underpin
clonal evolution and the breeding of asexual crops. Sweet orange is a model species for …
clonal evolution and the breeding of asexual crops. Sweet orange is a model species for …
