The health burden of cancer is increasing in China, with more than 1·6 million people being
diagnosed and 1·2 million people dying of the disease each year. As in most other countries, …

The 13th St Gallen International Breast Cancer Conference (2013) Expert Panel reviewed
and endorsed substantial new evidence on aspects of the local and regional therapies for …

The 14th St Gallen International Breast Cancer Conference (2015) reviewed substantial
new evidence on locoregional and systemic therapies for early breast cancer. Further …

The tumor microenvironment is highly complex, and immune escape is currently considered
an important hallmark of cancer, largely contributing to tumor progression and metastasis. …

Autophagy is a cellular response to adverse environment and stress, but its significance in
cell survival is not always clear. Here we show that autophagy could be induced in the …

We comprehensively analyzed clinical, genomic, and transcriptomic data of a cohort of 465
primary triple-negative breast cancer (TNBC). PIK3CA mutations and copy-number gains of …

Treatment of triple-negative breast cancer (TNBC) remains challenging. Deciphering the
orchestration of metabolic pathways in regulating ferroptosis will provide new insights into …

Triple-negative breast cancer (TNBC) remains an unmet medical challenge. We investigated
metabolic dysregulation in TNBCs by using our multi-omics database (n = 465, the largest …

Tumors are not only aggregates of malignant cells but also well-organized complex
ecosystems. The immunological components within tumors, termed the tumor immune …

Immunotherapy has achieved limited success in patients with triple-negative breast cancer (TNBC),
an aggressive disease with a poor prognosis. Commensal microbiota have been …