[HTML][HTML] CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis

Y Guo, Z Zhu, Z Huang, L Cui, W Yu, W Hong… - Nature …, 2022 - nature.com
Dysregulation of Hippo pathway leads to hyperactivation of YAP-TEAD transcriptional
complex in various cancers, including colorectal cancer (CRC). In this study, we observed that …

LAMB3 promotes tumour progression through the AKT–FOXO3/4 axis and is transcriptionally regulated by the BRD2/acetylated ELK4 complex in colorectal cancer

Z Zhu, J Song, Y Guo, Z Huang, X Chen, X Dang… - Oncogene, 2020 - nature.com
Aberrant expression of laminin-332 promotes tumour growth and metastasis in multiple
cancers. However, the dysregulated expression and mechanism of action of LAMB3, which …

Reduced risk of inflammatory bowel disease-associated colorectal neoplasia with use of thiopurines: a systematic review and meta-analysis

Z Zhu, Z Mei, Y Guo, G Wang, T Wu… - Journal of Crohn's …, 2018 - academic.oup.com
Background and Aims The association between thiopurines and colorectal neoplasia risk
remains controversial in inflammatory bowel disease [IBD] patients. We performed a …

[HTML][HTML] Small-molecule activating SIRT6 elicits therapeutic effects and synergistically promotes anti-tumor activity of vitamin D3 in colorectal cancer

J Shang, Z Zhu, Y Chen, J Song, Y Huang, K Song… - Theranostics, 2020 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the leading cause of cancer death; however, targets with broad
anti-CRC effects are limited. Sirtuin6 (SIRT6) is a conserved nicotinamide adenine …

[HTML][HTML] Co-inhibition of BET proteins and NF-κB as a potential therapy for colorectal cancer through synergistic inhibiting MYC and FOXM1 expressions

T Wu, G Wang, W Chen, Z Zhu, Y Liu, Z Huang… - Cell death & …, 2018 - nature.com
The bromodomain and extra-terminal domain inhibitors (BETi) are promising epigenetic drugs
for the treatment of various cancers through suppression of oncogenic transcription factors…

[HTML][HTML] Small heat shock protein CRYAB inhibits intestinal mucosal inflammatory responses and protects barrier integrity through suppressing IKKβ activity

…, H Zhao, M Zhou, Y Huang, D Wen, J Song, Z Zhu… - Mucosal …, 2019 - Elsevier
Alpha B-crystallin (CRYAB) is an important member of the small heat shock protein family,
and plays a protective and therapeutic role in neurological inflammation. CRYAB expression …

Pulse density modulation based mutual inductance and load resistance identification method for wireless power transfer system

R Dai, W Zhou, Y Chen, Z Zhu… - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
In wireless power transfer (WPT) system, the information of mutual inductance and load
resistance is usually needed for the front-end to regulate power and efficiency. To acquire the …

[HTML][HTML] Increased AOC1 expression promotes cancer progression in colorectal cancer

…, W Tang, Z Huang, Z Zhu, W Ding, J Fu, Y Zhu… - Frontiers in …, 2021 - frontiersin.org
Background Amine oxidase copper containing 1 (AOC1) is a gene whose biological function
in colorectal cancer (CRC) has not been elucidated. Therefore, the purpose of this study …

Simulation of active steering control for the prevention of tractor dynamic rollover on random road surfaces

J Qin, Z Zhu, H Ji, Z Zhu, Z Li, Y Du, Z Song… - Biosystems …, 2019 - Elsevier
… Author links open overlay panel Jiahao Qin a b , Zhehui Zhu a , Hongyi Ji a b ,
Zhongxiang Zhu a b , Zhen Li a b , Yuefeng Du a b , Zhenghe Song a b , Enrong Mao a b …

[HTML][HTML] ELK4 exerts opposite roles in cytokine/chemokine production and degranulation in activated mast cells

Y Huang, Z Zhu, W Li, Y Ge, Y Li, J Wang… - Frontiers in …, 2023 - frontiersin.org
The proliferative potential of mast cells after activation for 3-4h was found to be decreased,
which suggests that mast cell degranulation and cell proliferation are differentially regulated. …